[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr7:2,032,803-3,581,391

Best TWAS P=1.13e-29 · Best GWAS P=2.19e-29 conditioned to 0.0124

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-11.2	11.3	1.1e-29	-0.90	0.01	0.99	TRUE
4	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-11.3	-11.2	2.7e-29	0.99	0.00	1.00	FALSE
17	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-10.8	-10.9	6.7e-28	0.94	0.02	0.91	FALSE
10	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-11.2	-10.9	1.8e-27	0.94	0.01	0.99	FALSE
9	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-11.0	-10.3	1.2e-24	0.87	0.02	0.98	FALSE
3	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-11.2	-9.7	3.8e-22	0.84	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	6.7	-9.6	1.4e-21	0.71	0.01	0.70	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-7.2	-9.5	1.5e-21	0.86	0.04	0.95	FALSE
6	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-7.1	-9.5	2.0e-21	0.87	0.02	0.92	FALSE
12	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-7.3	-9.3	1.0e-20	0.86	0.75	0.25	FALSE
5	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-11.2	-9.3	2.0e-20	0.86	0.02	0.98	FALSE
14	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-7.0	-9.2	2.9e-20	0.87	0.13	0.87	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	4.6	-9.2	4.8e-20	0.78	0.06	0.74	FALSE
11	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-10.9	-9.2	5.6e-20	0.78	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	-7.2	-7.9	2.5e-15	0.76	0.10	0.90	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	AMZ1	0.04	0.04	lasso	3	0.02	1.3e-03	6.7	7.8	5.3e-15	-0.60	0.03	0.92	FALSE
15	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	-7.1	-7.8	6.6e-15	0.72	0.05	0.82	FALSE
19	NTR	Blood	GNA12	0.07	0.03	bslmm	597	0.06	1.3e-17	-8.0	-7.8	8.4e-15	0.63	0.89	0.11	FALSE
18	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	-7.1	-7.2	4.1e-13	0.72	0.26	0.74	FALSE
16	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	-7.1	-7.2	4.5e-13	0.70	0.26	0.73	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	-7.2	-7.2	5.0e-13	0.72	0.07	0.78	FALSE
21	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	4.9	-6.9	6.0e-12	0.52	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	5.3	6.6	4.2e-11	-0.43	1.00	0.00	FALSE
7	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	5.6	-6.5	8.9e-11	0.58	0.31	0.66	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	5.4	-6.0	1.5e-09	0.54	0.30	0.69	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMZ1	0.08	0.01	blup	71	0.05	1.3e-05	-7.2	5.5	4.5e-08	-0.60	0.05	0.77	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	AMZ1	0.32	0.04	enet	19	0.20	3.3e-19	-8.0	5.3	1.4e-07	-0.52	0.16	0.84	FALSE