[Hub]/) : Traits : Arm fat-free mass (right) :

chr10:69,348,758-70,981,217

Best TWAS P=1.19e-13 · Best GWAS P=5.82e-16 conditioned to 0.000955

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DNA2 0.32 0.18 lasso 9 0.20 1.9e-10 -5.3 5.5 4.8e-08 0.34 1.00 0.00 FALSE
2 GTEx Artery Aorta DNA2 0.22 0.17 lasso 6 0.16 5.1e-09 -4.6 5.2 2.3e-07 0.32 1.00 0.00 FALSE
3 GTEx Artery Coronary DNA2 0.12 0.12 lasso 5 0.12 5.3e-05 -5.2 5.7 1.3e-08 0.35 0.31 0.19 FALSE
4 GTEx Brain Cerebellum SLC25A16 0.22 0.15 lasso 9 0.19 2.2e-06 -4.6 -5.2 1.8e-07 -0.33 0.32 0.04 FALSE
5 GTEx Brain Hypothalamus SLC25A16 0.20 0.19 lasso 5 0.14 3.6e-04 -5.3 -5.3 1.1e-07 -0.32 0.15 0.05 FALSE
6 GTEx Cells EBV-transformed lymphocytes DNA2 0.32 0.14 lasso 2 0.10 2.9e-04 -5.3 5.3 1.2e-07 0.33 0.46 0.03 FALSE
7 GTEx Cells Transformed fibroblasts SLC25A16 0.10 0.02 enet 25 0.01 2.5e-02 -4.3 -6.6 4.2e-11 -0.54 0.70 0.20 FALSE
8 GTEx Heart Atrial Appendage PBLD 0.08 0.02 lasso 2 0.02 6.1e-02 -6.4 -6.9 6.7e-12 -0.41 0.11 0.09 FALSE
9 GTEx Lung DNA2 0.22 0.17 enet 12 0.24 3.9e-18 -5.2 5.4 8.3e-08 0.35 1.00 0.00 FALSE
10 GTEx Ovary DNA2 0.15 0.12 lasso 3 0.06 1.7e-02 -5.2 5.3 9.0e-08 0.34 0.12 0.05 FALSE
11 GTEx Pancreas DNA2 0.12 0.06 enet 9 0.08 4.1e-04 -4.3 5.8 8.5e-09 0.40 0.36 0.32 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic DNA2 0.29 0.16 lasso 14 0.22 2.4e-12 -4.6 5.4 6.6e-08 0.32 1.00 0.00 FALSE
13 NTR Blood SLC25A16 0.03 0.02 enet 16 0.03 1.7e-09 -5.2 -5.6 2.1e-08 -0.41 1.00 0.00 FALSE
14 ROSMAP Brain Pre-frontal Cortex SLC25A16 0.17 0.11 lasso 6 0.15 2.9e-19 -4.3 -5.6 2.3e-08 -0.33 1.00 0.00 FALSE
15 YFS Blood SLC25A16 0.09 0.13 lasso 3 0.13 6.8e-39 -5.2 -5.6 2.4e-08 -0.35 1.00 0.00 TRUE
16 The Cancer Genome Atlas Bladder Urothelial Carcinoma PBLD 0.06 0.07 lasso 2 0.04 2.3e-04 -6.0 -6.0 2.5e-09 -0.32 0.01 0.98 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma SLC25A16 0.01 0.02 lasso 2 0.01 5.5e-04 -5.3 -5.3 1.3e-07 -0.33 0.34 0.06 FALSE
18 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DNA2 0.08 0.09 lasso 1 0.06 7.3e-04 -6.5 6.5 9.2e-11 0.39 0.00 0.97 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATOH7 0.05 0.01 lasso 3 0.02 2.6e-03 -5.9 5.2 2.2e-07 0.26 0.01 0.81 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PBLD 0.03 0.03 lasso 9 0.02 1.6e-03 -5.1 -5.1 2.7e-07 -0.26 0.04 0.66 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PBLD 0.10 0.03 lasso 3 0.04 2.2e-05 -6.0 -5.6 1.7e-08 -0.31 0.02 0.98 FALSE
22 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DNA2 0.05 0.00 blup 43 0.00 3.0e-01 -5.4 5.9 3.6e-09 0.39 0.02 0.71 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma PBLD 0.12 0.18 enet 10 0.18 6.7e-20 -4.5 -5.3 1.1e-07 -0.35 0.39 0.61 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma SLC25A16 0.05 0.01 blup 42 0.02 2.9e-03 -5.4 -6.2 4.7e-10 -0.51 0.11 0.71 FALSE
25 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC25A16 0.02 0.02 enet 8 0.02 7.7e-04 -6.5 -6.3 4.1e-10 -0.38 0.09 0.03 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma PBLD 0.03 0.01 blup 76 0.01 1.3e-02 -5.0 -5.2 1.6e-07 -0.30 0.06 0.34 FALSE
27 The Cancer Genome Atlas Soft Tissue Sarcoma SLC25A16 0.07 0.03 blup 42 0.02 1.7e-02 -6.5 -7.4 1.2e-13 -0.53 0.12 0.16 TRUE
28 The Cancer Genome Atlas Testicular Germ Cell Tumors DNA2 0.14 0.07 blup 43 0.08 8.6e-04 -5.5 -5.9 4.0e-09 -0.39 0.07 0.51 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma SLC25A16 0.05 0.05 lasso 3 0.04 3.8e-05 -5.2 -5.5 4.5e-08 -0.36 0.30 0.10 FALSE