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chr13:49,409,343-52,109,040

Best TWAS P=4.81e-26 · Best GWAS P=8.53e-49 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	NTR	Blood	DLEU7	0.07	0.02	enet	22	0.06	1.3e-19	-7.05	-10.6	4.8e-26	0.61	0.11	0.89	TRUE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	6.92	7.5	7.8e-14	-0.10	0.01	0.96	TRUE
21	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	5.24	-6.4	1.7e-10	0.06	0.01	0.98	TRUE
14	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	5.30	-6.3	2.2e-10	0.03	1.00	0.00	TRUE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	5.24	-5.9	3.4e-09	0.04	0.01	0.89	TRUE
12	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	5.54	-5.8	8.0e-09	0.02	1.00	0.00	TRUE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EBPL	0.27	0.16	blup	59	0.22	1.0e-12	-1.14	-5.6	1.7e-08	0.06	0.29	0.71	TRUE
7	GTEx	Brain Cortex	EBPL	0.36	0.08	enet	24	0.14	1.5e-04	6.79	-5.4	6.4e-08	0.14	0.18	0.15	TRUE
10	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	7.00	7.3	3.2e-13	-0.11	0.51	0.02	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DLEU7	0.05	0.00	blup	581	0.02	1.6e-03	1.35	6.2	7.5e-10	-0.46	0.08	0.21	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	6.79	-6.1	1.3e-09	0.07	0.00	1.00	FALSE
5	GTEx	Artery Aorta	EBPL	0.43	0.20	enet	78	0.28	8.1e-16	5.19	-6.1	1.4e-09	0.14	1.00	0.00	FALSE
11	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	6.79	-5.9	3.9e-09	0.07	0.38	0.04	FALSE
6	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	6.79	-5.8	6.4e-09	0.05	0.86	0.01	FALSE
4	GTEx	Adipose Visceral Omentum	EBPL	0.27	0.03	enet	17	0.20	1.4e-10	6.79	-5.7	1.2e-08	0.09	0.88	0.01	FALSE
15	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	5.12	-5.7	1.6e-08	0.08	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DLEU2	0.08	0.02	lasso	2	0.01	1.6e-02	-5.45	5.6	1.7e-08	0.02	0.13	0.25	FALSE
2	CommonMind	Brain Pre-frontal Cortex	EBPL	0.34	0.16	bslmm	399	0.33	2.5e-41	0.34	-5.5	2.9e-08	0.04	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	7.05	-5.5	3.6e-08	0.06	0.00	0.46	FALSE
13	GTEx	Spleen	RCBTB1	0.37	0.02	lasso	5	0.04	3.5e-02	0.85	-5.5	4.9e-08	0.01	0.04	0.10	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TRIM13	0.15	0.04	lasso	5	0.12	1.1e-14	6.82	-5.4	6.2e-08	0.22	1.00	0.00	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	5.12	-5.3	9.1e-08	0.02	1.00	0.00	FALSE
9	GTEx	Esophagus Muscularis	EBPL	0.39	0.16	enet	36	0.29	9.2e-18	5.19	-5.3	1.4e-07	0.03	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Stomach Adenocarcinoma	EBPL	0.10	0.07	enet	7	0.08	2.8e-06	6.79	-5.2	1.6e-07	0.12	0.00	1.00	FALSE