Best TWAS P=1.2e-11 · Best GWAS P=1.79e-11 conditioned to 0.15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | -5.8 | 5.9 | 3.6e-09 | -0.61 | 0.31 | 0.67 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | -6.7 | 6.8 | 1.2e-11 | -0.90 | 0.01 | 0.55 | TRUE |