Best TWAS P=1.65e-09 · Best GWAS P=1.98e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ARID3B | 0.05 | 0.03 | bslmm | 367 | 0.03 | 0.00014 | -3.5 | -5.2 | 1.7e-07 | 0.19 | 0.13 | 0.23 | TRUE |
2 | GTEx | Adrenal Gland | SNUPN | 0.17 | 0.05 | enet | 17 | 0.11 | 0.00013 | -3.8 | 6.0 | 1.7e-09 | -0.09 | 0.02 | 0.16 | TRUE |
3 | GTEx | Nerve Tibial | CYP11A1 | 0.06 | 0.00 | lasso | 2 | 0.00 | 0.59100 | -5.2 | -5.2 | 1.9e-07 | 1.00 | 0.00 | 0.99 | TRUE |