Best TWAS P=6.6e-11 · Best GWAS P=1.83e-13 conditioned to 1.36e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | ADAM17 | 0.20 | 0.14 | lasso | 5 | 0.15 | 7.8e-05 | -5.2 | 5.2 | 2.3e-07 | 0.22 | 0.51 | 0.03 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RP11-254F7.2 | 0.35 | 0.21 | bslmm | 562 | 0.30 | 1.4e-39 | 5.6 | 6.5 | 6.6e-11 | 0.05 | 0.99 | 0.01 | TRUE |