TWAS
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Genes
Traits
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Traits
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Arm fat-free mass (right)
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chr17:1,717,695-2,453,908
Best TWAS P=8.47e-08 · Best GWAS P=1.6e-08 conditioned to 0.000753
1.7M
1.8M
1.9M
2M
2.1M
2.2M
2.3M
2.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
SMG6
0.03
0.01
blup
144
0.01
0.00478
3.8
5.4
8.5e-08
-0.52
0.12
0.47
TRUE
2
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SMG6
0.08
0.05
blup
144
0.07
0.00013
4.6
5.2
2.6e-07
-0.53
0.36
0.42
FALSE