[Hub]/) : Traits : Arm fat-free mass (right) :

chr16:88,074,533-90,172,696

Best TWAS P=3.39e-12 · Best GWAS P=1.42e-12 conditioned to 3.22e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CTU2 0.10 0.07 lasso 5 0.08 4.0e-10 -4.6 5.3 1.3e-07 -0.43 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex SPG7 0.14 0.06 blup 445 0.10 3.2e-12 5.4 -5.4 8.4e-08 -0.02 0.04 0.96 FALSE
3 GTEx Artery Aorta RPL13 0.19 0.20 lasso 5 0.17 1.7e-09 5.0 -5.8 5.9e-09 0.05 0.07 0.93 FALSE
4 GTEx Brain Cerebellar Hemisphere AC092143.1 0.20 0.01 enet 22 0.06 9.7e-03 1.8 5.2 2.5e-07 0.03 0.07 0.22 FALSE
5 GTEx Breast Mammary Tissue RPL13 0.09 0.05 enet 7 0.04 5.3e-03 5.9 -6.2 5.0e-10 0.00 0.05 0.88 FALSE
6 GTEx Cells Transformed fibroblasts RPL13 0.10 0.08 enet 8 0.09 3.7e-07 4.6 -5.7 1.6e-08 0.09 0.10 0.89 TRUE
7 GTEx Cells Transformed fibroblasts RP11-104N10.1 0.07 0.10 lasso 2 0.08 8.3e-07 -5.4 -5.4 6.0e-08 -0.17 0.15 0.84 FALSE
8 GTEx Colon Sigmoid CDK10 0.37 0.12 lasso 8 0.22 2.2e-08 3.3 -5.4 5.3e-08 -0.21 0.18 0.71 FALSE
9 GTEx Colon Sigmoid RP11-104N10.1 0.14 0.00 lasso 2 0.02 8.3e-02 -5.6 -5.7 1.4e-08 -0.17 0.06 0.48 TRUE
10 GTEx Colon Transverse RPL13 0.23 0.17 lasso 4 0.16 3.7e-08 5.8 -7.0 3.4e-12 0.01 0.03 0.97 TRUE
11 GTEx Esophagus Muscularis RPL13 0.17 0.12 lasso 3 0.11 2.4e-07 5.8 -6.1 1.3e-09 0.06 0.03 0.97 TRUE
12 GTEx Muscle Skeletal RPL13 0.10 0.09 lasso 5 0.10 3.3e-10 5.0 -5.3 1.1e-07 0.08 0.08 0.92 FALSE
13 GTEx Muscle Skeletal SPG7 0.24 0.22 lasso 5 0.23 8.9e-23 -5.4 -6.2 5.4e-10 -0.11 0.19 0.81 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic RPL13 0.16 0.15 lasso 4 0.15 2.0e-08 5.4 -5.5 5.0e-08 0.09 0.12 0.88 TRUE
15 GTEx Skin Not Sun Exposed Suprapubic RP11-104N10.1 0.11 0.04 lasso 4 0.03 5.2e-03 -5.6 -5.7 1.3e-08 -0.13 0.09 0.67 FALSE
16 GTEx Skin Sun Exposed Lower leg SPG7 0.09 0.05 lasso 2 0.03 1.5e-03 5.8 -5.6 2.3e-08 0.08 0.06 0.94 FALSE
17 GTEx Testis RP5-1142A6.2 0.21 0.13 lasso 4 0.12 7.2e-06 -5.7 -6.7 2.9e-11 0.60 0.15 0.34 TRUE
18 GTEx Thyroid RPL13 0.13 0.05 enet 10 0.06 1.4e-05 5.6 -6.6 3.1e-11 -0.02 0.06 0.93 FALSE
19 GTEx Whole Blood ANKRD11 0.07 0.05 lasso 2 0.04 2.4e-04 5.2 -5.2 1.6e-07 -0.08 0.12 0.85 FALSE
20 GTEx Whole Blood SPG7 0.06 0.05 lasso 3 0.05 3.9e-05 5.4 -6.2 6.1e-10 0.01 0.09 0.86 FALSE
21 GTEx Whole Blood CTD-2555A7.3 0.10 0.00 lasso 5 0.01 1.0e-01 3.0 5.9 3.3e-09 -0.19 0.10 0.33 TRUE
22 METSIM Adipose RPL13 0.05 0.05 enet 5 0.05 1.0e-07 5.5 -5.5 4.5e-08 0.07 0.07 0.93 FALSE
23 YFS Blood SPG7 0.08 0.11 lasso 6 0.11 6.9e-34 -5.6 -5.7 1.5e-08 -0.18 0.13 0.87 FALSE
24 The Cancer Genome Atlas Bladder Urothelial Carcinoma SPG7 0.05 0.03 lasso 3 0.03 1.8e-03 5.3 -5.3 1.5e-07 0.08 0.06 0.60 FALSE
25 The Cancer Genome Atlas Esophageal Carcinoma RPL13 0.14 0.07 lasso 3 0.04 2.6e-02 5.3 -5.5 4.0e-08 0.07 0.03 0.54 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SPG7 0.05 0.05 lasso 5 0.05 1.9e-06 5.3 -5.4 7.9e-08 0.08 0.13 0.87 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma SPG7 0.03 0.02 blup 58 0.03 4.1e-04 4.6 -6.3 3.2e-10 -0.01 0.05 0.50 TRUE
28 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPL13 0.03 0.01 blup 41 0.02 8.5e-03 5.2 -6.1 9.2e-10 0.01 0.03 0.51 FALSE
29 The Cancer Genome Atlas Pancreatic Adenocarcinoma SPG7 0.11 0.09 lasso 2 0.08 2.5e-04 5.7 -5.7 1.2e-08 0.07 0.07 0.81 FALSE
30 The Cancer Genome Atlas Stomach Adenocarcinoma RPL13 0.04 0.03 blup 41 0.03 2.2e-03 5.0 -6.1 1.3e-09 0.06 0.04 0.63 FALSE