[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr16:88,074,533-90,172,696

Best TWAS P=3.39e-12 · Best GWAS P=1.42e-12 conditioned to 3.22e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Colon Transverse	RPL13	0.23	0.17	lasso	4	0.16	3.7e-08	5.8	-7.0	3.4e-12	0.01	0.03	0.97	TRUE
17	GTEx	Testis	RP5-1142A6.2	0.21	0.13	lasso	4	0.12	7.2e-06	-5.7	-6.7	2.9e-11	0.60	0.15	0.34	TRUE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	SPG7	0.03	0.02	blup	58	0.03	4.1e-04	4.6	-6.3	3.2e-10	-0.01	0.05	0.50	TRUE
11	GTEx	Esophagus Muscularis	RPL13	0.17	0.12	lasso	3	0.11	2.4e-07	5.8	-6.1	1.3e-09	0.06	0.03	0.97	TRUE
21	GTEx	Whole Blood	CTD-2555A7.3	0.10	0.00	lasso	5	0.01	1.0e-01	3.0	5.9	3.3e-09	-0.19	0.10	0.33	TRUE
9	GTEx	Colon Sigmoid	RP11-104N10.1	0.14	0.00	lasso	2	0.02	8.3e-02	-5.6	-5.7	1.4e-08	-0.17	0.06	0.48	TRUE
6	GTEx	Cells Transformed fibroblasts	RPL13	0.10	0.08	enet	8	0.09	3.7e-07	4.6	-5.7	1.6e-08	0.09	0.10	0.89	TRUE
14	GTEx	Skin Not Sun Exposed Suprapubic	RPL13	0.16	0.15	lasso	4	0.15	2.0e-08	5.4	-5.5	5.0e-08	0.09	0.12	0.88	TRUE
18	GTEx	Thyroid	RPL13	0.13	0.05	enet	10	0.06	1.4e-05	5.6	-6.6	3.1e-11	-0.02	0.06	0.93	FALSE
5	GTEx	Breast Mammary Tissue	RPL13	0.09	0.05	enet	7	0.04	5.3e-03	5.9	-6.2	5.0e-10	0.00	0.05	0.88	FALSE
13	GTEx	Muscle Skeletal	SPG7	0.24	0.22	lasso	5	0.23	8.9e-23	-5.4	-6.2	5.4e-10	-0.11	0.19	0.81	FALSE
20	GTEx	Whole Blood	SPG7	0.06	0.05	lasso	3	0.05	3.9e-05	5.4	-6.2	6.1e-10	0.01	0.09	0.86	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPL13	0.03	0.01	blup	41	0.02	8.5e-03	5.2	-6.1	9.2e-10	0.01	0.03	0.51	FALSE
30	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPL13	0.04	0.03	blup	41	0.03	2.2e-03	5.0	-6.1	1.3e-09	0.06	0.04	0.63	FALSE
3	GTEx	Artery Aorta	RPL13	0.19	0.20	lasso	5	0.17	1.7e-09	5.0	-5.8	5.9e-09	0.05	0.07	0.93	FALSE
29	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SPG7	0.11	0.09	lasso	2	0.08	2.5e-04	5.7	-5.7	1.2e-08	0.07	0.07	0.81	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	RP11-104N10.1	0.11	0.04	lasso	4	0.03	5.2e-03	-5.6	-5.7	1.3e-08	-0.13	0.09	0.67	FALSE
23	YFS	Blood	SPG7	0.08	0.11	lasso	6	0.11	6.9e-34	-5.6	-5.7	1.5e-08	-0.18	0.13	0.87	FALSE
16	GTEx	Skin Sun Exposed Lower leg	SPG7	0.09	0.05	lasso	2	0.03	1.5e-03	5.8	-5.6	2.3e-08	0.08	0.06	0.94	FALSE
25	The Cancer Genome Atlas	Esophageal Carcinoma	RPL13	0.14	0.07	lasso	3	0.04	2.6e-02	5.3	-5.5	4.0e-08	0.07	0.03	0.54	FALSE
22	METSIM	Adipose	RPL13	0.05	0.05	enet	5	0.05	1.0e-07	5.5	-5.5	4.5e-08	0.07	0.07	0.93	FALSE
8	GTEx	Colon Sigmoid	CDK10	0.37	0.12	lasso	8	0.22	2.2e-08	3.3	-5.4	5.3e-08	-0.21	0.18	0.71	FALSE
7	GTEx	Cells Transformed fibroblasts	RP11-104N10.1	0.07	0.10	lasso	2	0.08	8.3e-07	-5.4	-5.4	6.0e-08	-0.17	0.15	0.84	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPG7	0.05	0.05	lasso	5	0.05	1.9e-06	5.3	-5.4	7.9e-08	0.08	0.13	0.87	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SPG7	0.14	0.06	blup	445	0.10	3.2e-12	5.4	-5.4	8.4e-08	-0.02	0.04	0.96	FALSE
12	GTEx	Muscle Skeletal	RPL13	0.10	0.09	lasso	5	0.10	3.3e-10	5.0	-5.3	1.1e-07	0.08	0.08	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CTU2	0.10	0.07	lasso	5	0.08	4.0e-10	-4.6	5.3	1.3e-07	-0.43	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SPG7	0.05	0.03	lasso	3	0.03	1.8e-03	5.3	-5.3	1.5e-07	0.08	0.06	0.60	FALSE
19	GTEx	Whole Blood	ANKRD11	0.07	0.05	lasso	2	0.04	2.4e-04	5.2	-5.2	1.6e-07	-0.08	0.12	0.85	FALSE
4	GTEx	Brain Cerebellar Hemisphere	AC092143.1	0.20	0.01	enet	22	0.06	9.7e-03	1.8	5.2	2.5e-07	0.03	0.07	0.22	FALSE