Best TWAS P=1.48e-12 · Best GWAS P=2.79e-13 conditioned to 0.000239
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Esophageal Carcinoma | HOXD12 | 0.21 | 0.05 | blup | 48 | 0.13 | 6.3e-05 | 6.3 | -7.1 | 1.5e-12 | -0.63 | 0.01 | 0.61 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXD11 | 0.03 | 0.02 | enet | 7 | 0.03 | 5.8e-04 | 6.8 | -7.0 | 1.9e-12 | -0.78 | 0.01 | 0.93 | FALSE |