Best TWAS P=2.17e-09 · Best GWAS P=1.5e-07 conditioned to 0.0456
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Prostate | MLPH | 0.33 | 0.02 | enet | 26 | 0.12 | 5.9e-04 | -1.3 | 6.0 | 2.2e-09 | -0.61 | 0.06 | 0.49 | TRUE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MLPH | 0.10 | 0.10 | lasso | 1 | 0.08 | 4.4e-09 | -5.2 | 5.2 | 2.5e-07 | -0.95 | 0.01 | 0.98 | FALSE |