[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr2:241,563,169-243,048,760

Best TWAS P=3.38e-10 · Best GWAS P=5.3e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Adipose Visceral Omentum	BOK	0.20	0.12	lasso	4	0.12	1.4e-06	-6.2	-6.3	3.4e-10	0.97	0.00	1.00	TRUE
3	GTEx	Adipose Subcutaneous	AC005104.3	0.12	0.03	lasso	5	0.06	1.5e-05	4.8	6.0	2.4e-09	-0.06	0.46	0.16	TRUE
18	GTEx	Skin Not Sun Exposed Suprapubic	AC005104.3	0.27	0.06	enet	24	0.20	5.6e-11	3.8	5.9	3.1e-09	-0.21	0.58	0.06	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	SEPT2	0.66	0.38	enet	29	0.50	7.1e-21	4.8	5.8	5.2e-09	-0.08	0.78	0.22	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	SEPT2	0.63	0.38	enet	29	0.42	1.1e-24	4.8	5.8	5.8e-09	-0.08	0.78	0.22	FALSE
2	GTEx	Adipose Subcutaneous	SEPT2	0.45	0.36	enet	32	0.43	3.0e-38	4.8	5.8	6.3e-09	-0.08	0.78	0.22	FALSE
21	METSIM	Adipose	BOK	0.06	0.03	lasso	6	0.03	7.8e-06	-6.2	-5.8	6.3e-09	0.95	0.00	1.00	FALSE
23	NTR	Blood	SEPT2	0.18	0.10	enet	34	0.14	1.0e-43	4.8	5.8	6.8e-09	-0.13	0.78	0.22	FALSE
8	GTEx	Breast Mammary Tissue	SEPT2	0.46	0.33	enet	37	0.35	5.2e-19	4.8	5.8	7.8e-09	-0.08	0.78	0.22	FALSE
7	GTEx	Brain Frontal Cortex BA9	SEPT2	0.30	-0.01	enet	32	0.02	1.1e-01	4.8	5.7	1.4e-08	-0.13	0.07	0.06	FALSE
16	GTEx	Ovary	SEPT2	0.56	0.29	lasso	5	0.23	2.4e-06	4.8	5.6	2.6e-08	-0.06	0.42	0.14	FALSE
14	GTEx	Muscle Skeletal	SEPT2	0.39	0.22	enet	46	0.26	1.0e-25	4.8	5.6	2.8e-08	-0.13	0.78	0.22	FALSE
12	GTEx	Esophagus Muscularis	SEPT2	0.57	0.34	enet	34	0.48	1.7e-32	4.8	5.5	2.9e-08	-0.11	0.78	0.21	FALSE
11	GTEx	Esophagus Mucosa	SEPT2	0.59	0.50	enet	37	0.56	2.7e-44	4.8	5.5	3.0e-08	-0.06	0.78	0.22	FALSE
9	GTEx	Cells Transformed fibroblasts	SEPT2	0.34	0.14	lasso	6	0.32	5.5e-25	4.8	5.5	4.6e-08	-0.09	0.78	0.22	FALSE
15	GTEx	Nerve Tibial	AC005104.3	0.28	0.21	enet	19	0.24	4.6e-17	4.8	5.5	5.0e-08	-0.06	0.78	0.22	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	BOK	0.07	0.04	lasso	5	0.03	1.8e-04	5.6	-5.4	5.7e-08	0.76	0.01	0.97	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	SEPT2	0.24	0.04	blup	45	0.08	1.6e-09	2.5	5.4	7.0e-08	-0.12	0.00	0.02	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	SEPT2	0.48	0.39	enet	49	0.42	6.0e-58	4.8	5.4	8.5e-08	-0.10	0.78	0.22	FALSE
27	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SEPT2	0.42	0.11	enet	14	0.18	5.2e-08	2.4	5.3	1.2e-07	-0.07	0.00	0.01	FALSE
13	GTEx	Lung	SEPT2	0.42	0.33	lasso	6	0.38	2.6e-30	4.8	5.3	1.4e-07	-0.04	0.78	0.22	FALSE
20	GTEx	Whole Blood	SEPT2	0.26	0.10	lasso	5	0.12	1.8e-11	4.8	5.3	1.4e-07	-0.08	0.78	0.22	FALSE
19	GTEx	Skin Sun Exposed Lower leg	SEPT2	0.55	0.36	lasso	9	0.37	7.6e-32	4.8	5.2	1.6e-07	-0.04	0.78	0.22	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SEPT2	0.19	0.06	enet	9	0.08	1.0e-09	2.5	5.2	1.6e-07	-0.10	0.00	0.02	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SEPT2	0.52	0.29	bslmm	377	0.44	2.0e-59	4.9	5.2	2.4e-07	-0.12	0.78	0.22	FALSE
5	GTEx	Artery Aorta	SEPT2	0.60	0.38	lasso	9	0.46	5.8e-28	4.8	5.2	2.4e-07	-0.08	0.78	0.22	FALSE
28	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	BOK	0.19	-0.01	lasso	4	0.01	1.2e-01	-6.2	-5.1	2.7e-07	0.86	0.00	0.76	FALSE
6	GTEx	Artery Tibial	SEPT2	0.58	0.50	lasso	13	0.58	1.4e-55	4.8	5.1	2.9e-07	-0.06	0.78	0.22	FALSE
22	METSIM	Adipose	SEPT2	0.29	0.21	bslmm	375	0.20	1.6e-29	4.8	5.1	2.9e-07	-0.04	0.78	0.22	FALSE