Best TWAS P=7.69e-09 · Best GWAS P=2.56e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | RP11-738E22.3 | 0.07 | 0.04 | lasso | 6 | 0.05 | 7.7e-08 | -5.6 | 5.8 | 7.7e-09 | -0.98 | 0.01 | 0.99 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | REST | 0.04 | 0.02 | bslmm | 536 | 0.02 | 3.4e-03 | -5.4 | -5.7 | 9.2e-09 | 0.58 | 0.02 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -5.6 | -5.6 | 1.8e-08 | 0.86 | 0.01 | 0.96 | FALSE |