TWAS
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Traits
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Traits
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Arm fat-free mass (right)
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chr4:88,471,516-88,981,690
Best TWAS P=2.87e-10 · Best GWAS P=1.27e-12 conditioned to 0.000548
88.5M
88.6M
88.7M
88.8M
88.9M
89M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
IBSP
0.05
0.05
lasso
6
0.07
1.2e-13
-7.1
6.3
2.9e-10
-0.79
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
IBSP
0.08
0.00
blup
77
0.00
1.6e-01
-4.9
6.3
3.0e-10
-0.71
0.02
0.63
FALSE
5
The Cancer Genome Atlas
Lung Adenocarcinoma
IBSP
0.06
0.01
blup
78
0.03
7.7e-05
-7.1
6.1
1.1e-09
-0.75
0.00
0.99
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
IBSP
0.06
0.01
blup
78
0.03
8.2e-05
-5.0
5.5
3.9e-08
-0.55
0.02
0.87
FALSE
2
The Cancer Genome Atlas
Colon Adenocarcinoma
IBSP
0.09
0.02
enet
15
0.07
9.4e-05
-1.7
5.3
1.0e-07
-0.62
0.02
0.62
FALSE