[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr4:105,373,669-107,092,169

Best TWAS P=3.81e-18 · Best GWAS P=8.24e-20 conditioned to 0.000452

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Esophagus Gastroesophageal Junction	PPA2	0.29	0.15	lasso	5	0.14	8.8e-06	-8.6	-8.7	3.8e-18	0.81	0.07	0.88	TRUE
6	GTEx	Esophagus Mucosa	PPA2	0.18	0.06	enet	14	0.12	2.5e-08	6.8	-7.6	2.3e-14	0.68	0.12	0.87	FALSE
10	GTEx	Ovary	PPA2	0.18	0.10	lasso	3	0.14	2.2e-04	-6.1	-7.4	1.5e-13	0.72	0.07	0.61	FALSE
3	GTEx	Brain Cortex	PPA2	0.14	0.09	lasso	9	0.09	1.6e-03	-7.3	-7.3	2.7e-13	0.79	0.07	0.50	FALSE
12	The Cancer Genome Atlas	Thyroid Carcinoma	PPA2	0.04	0.02	blup	84	0.04	6.1e-05	-7.3	-6.6	3.6e-11	0.74	0.14	0.66	FALSE
4	GTEx	Cells Transformed fibroblasts	PPA2	0.11	0.03	lasso	3	0.01	6.5e-02	-6.0	-6.6	4.4e-11	0.59	0.42	0.10	FALSE
2	GTEx	Artery Aorta	PPA2	0.11	-0.01	enet	24	0.01	1.6e-01	-8.6	-6.5	7.0e-11	0.58	0.07	0.34	FALSE
9	GTEx	Nerve Tibial	PPA2	0.13	0.07	enet	23	0.07	2.1e-05	-6.1	-6.3	3.5e-10	0.63	0.52	0.22	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PPA2	0.08	0.03	bslmm	429	0.04	2.2e-05	-5.5	-6.2	6.3e-10	0.61	0.08	0.88	FALSE
7	GTEx	Heart Atrial Appendage	PPA2	0.15	0.05	lasso	7	0.06	7.4e-04	-7.4	-5.7	1.3e-08	0.70	0.24	0.37	FALSE
11	GTEx	Skin Sun Exposed Lower leg	TET2	0.09	0.01	enet	18	0.02	3.6e-03	-8.8	-5.5	3.3e-08	0.58	0.03	0.82	FALSE
8	GTEx	Muscle Skeletal	PPA2	0.19	0.06	enet	28	0.11	8.7e-11	-7.3	-5.2	2.1e-07	0.67	0.78	0.21	FALSE