Best TWAS P=3.59e-10 · Best GWAS P=1.54e-08 conditioned to 0.505
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | SH3D19 | 0.28 | 0.22 | lasso | 5 | 0.20 | 9.3e-06 | 5.3 | -5.2 | 1.8e-07 | 0.80 | 0.05 | 0.93 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | RP11-164P12.4 | 0.47 | 0.44 | enet | 18 | 0.35 | 6.6e-10 | 5.2 | 5.2 | 1.6e-07 | -0.81 | 0.06 | 0.94 | FALSE |
| 3 | GTEx | Spleen | RP11-164P12.4 | 0.36 | 0.26 | lasso | 10 | 0.20 | 5.8e-06 | 5.3 | 5.3 | 1.2e-07 | -0.82 | 0.06 | 0.92 | FALSE |
| 4 | NTR | Blood | FAM160A1 | 0.03 | 0.02 | enet | 26 | 0.02 | 1.4e-07 | -5.6 | 6.3 | 3.6e-10 | -0.94 | 0.02 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAM160A1 | 0.04 | 0.02 | blup | 99 | 0.02 | 1.2e-05 | 5.3 | 5.6 | 2.1e-08 | -0.91 | 0.03 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Colon Adenocarcinoma | FAM160A1 | 0.06 | 0.05 | lasso | 3 | 0.04 | 1.8e-03 | -5.6 | 5.4 | 6.6e-08 | -0.97 | 0.02 | 0.84 | FALSE |