Best TWAS P=3.09e-12 · Best GWAS P=8.28e-16 conditioned to 3.18e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | WDR70 | 0.06 | 0.03 | lasso | 8 | 0.03 | 0.0035 | -5.5 | 6.0 | 2.2e-09 | -0.72 | 0.38 | 0.42 | FALSE |
| 2 | GTEx | Whole Blood | C5orf42 | 0.07 | 0.00 | enet | 16 | 0.01 | 0.0183 | -8.1 | 5.7 | 1.4e-08 | -0.68 | 0.01 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C5orf42 | 0.04 | 0.05 | lasso | 3 | 0.04 | 0.0011 | -7.2 | 7.0 | 3.1e-12 | -0.92 | 0.00 | 0.94 | TRUE |