Best TWAS P=2.19e-31 · Best GWAS P=5.09e-40 conditioned to 0.463
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -10.3 | -8.5 | 2.8e-17 | 0.72 | 0.25 | 0.72 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 7.9 | 8.2 | 2.5e-16 | -0.57 | 0.04 | 0.46 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -11.3 | 11.1 | 1.6e-28 | -0.62 | 0.34 | 0.06 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 11.4 | -11.7 | 2.2e-31 | 0.64 | 0.32 | 0.53 | TRUE |