[Hub]/) : Traits : Arm fat-free mass (right) :

chr5:76,597,461-78,753,539

Best TWAS P=3.07e-20 · Best GWAS P=2.94e-19 conditioned to 0.0426

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Testis LHFPL2 0.18 -0.01 enet 21 0.10 2.1e-05 3.9 5.3 9.3e-08 -0.25 0.11 0.14 FALSE
2 METSIM Adipose AP3B1 0.07 0.01 blup 556 0.02 2.4e-04 4.2 -6.3 3.2e-10 0.53 0.10 0.77 FALSE
3 YFS Blood AP3B1 0.25 0.22 lasso 9 0.23 2.6e-74 5.2 -5.3 9.0e-08 0.31 1.00 0.00 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma AP3B1 0.02 0.00 blup 126 0.01 1.8e-02 -8.9 -9.2 3.1e-20 0.86 0.02 0.89 TRUE
5 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma AP3B1 0.16 0.06 enet 18 0.09 2.2e-05 6.1 -6.8 1.3e-11 0.53 0.04 0.54 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AP3B1 0.08 0.01 enet 20 0.02 9.7e-04 -8.6 -5.6 2.2e-08 0.58 0.02 0.80 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma AP3B1 0.05 0.03 lasso 3 0.04 4.4e-05 6.1 -5.7 1.6e-08 0.36 0.43 0.26 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma AP3B1 0.05 0.02 blup 126 0.03 5.0e-04 6.2 -8.5 1.3e-17 0.80 0.02 0.91 FALSE