[Hub]/) : Traits : Arm predicted mass (right) :

chr6:80,120,201-81,872,212

Best TWAS P=1.25e-18 · Best GWAS P=7.38e-16 conditioned to 0.056

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 6.7 -7.1 1.3e-12 -0.57 0.21 0.46 FALSE
2 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -7.2 -7.4 1.8e-13 -0.76 0.08 0.82 FALSE
3 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 5.1 -6.6 3.5e-11 -0.23 0.14 0.08 FALSE
4 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 4.4 7.9 3.2e-15 0.49 0.24 0.65 FALSE
5 GTEx Colon Transverse RP11-250B2.5 0.13 0.02 enet 3 0.01 6.3e-02 -2.4 -5.2 2.1e-07 -0.61 0.06 0.49 TRUE
6 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -7.1 -7.0 2.1e-12 -0.65 0.84 0.16 FALSE
7 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -4.0 -8.8 1.3e-18 -0.41 0.05 0.47 TRUE
8 GTEx Heart Left Ventricle RP11-250B2.6 0.09 0.00 enet 6 0.02 2.0e-02 7.3 -7.1 1.4e-12 -0.82 0.05 0.70 FALSE
9 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 4.4 -6.7 1.9e-11 -0.36 0.78 0.09 FALSE
10 GTEx Muscle Skeletal RP11-250B2.6 0.07 0.04 lasso 5 0.04 4.2e-05 7.7 -7.9 2.1e-15 -0.94 0.02 0.98 FALSE
11 GTEx Nerve Tibial BCKDHB 0.18 0.11 lasso 9 0.10 2.4e-07 5.1 5.1 2.7e-07 0.15 1.00 0.00 FALSE
12 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -7.1 -6.9 5.0e-12 -0.88 0.03 0.96 FALSE
13 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 4.4 6.1 1.3e-09 0.46 0.98 0.02 FALSE
14 METSIM Adipose RP11-250B2.6 0.04 0.04 lasso 12 0.02 1.7e-04 7.1 -6.2 6.0e-10 -0.60 0.62 0.18 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BCKDHB 0.12 0.06 lasso 4 0.06 4.2e-07 6.3 -5.8 7.0e-09 -0.75 0.45 0.54 FALSE