Best TWAS P=3.7e-18 · Best GWAS P=1.81e-19 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 0.00061 | -8.5 | 8.7 | 3.7e-18 | -0.97 | 0.02 | 0.96 | TRUE |
| 2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 0.00019 | -4.5 | 6.4 | 1.2e-10 | -0.74 | 0.11 | 0.89 | FALSE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 0.03380 | 3.7 | -5.4 | 6.6e-08 | 0.12 | 0.02 | 0.65 | TRUE |