[Hub]/) : Traits : Arm predicted mass (right) :

chr7:2,032,803-3,581,391

Best TWAS P=3.23e-31 · Best GWAS P=3.17e-30 conditioned to 0.0232

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 5.6 6.9 5.4e-12 -0.43 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous GNA12 0.11 0.08 lasso 4 0.07 1.3e-06 -7.1 -7.9 2.7e-15 0.76 0.14 0.86 FALSE
3 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -11.4 -9.8 1.0e-22 0.84 0.02 0.98 FALSE
4 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -11.4 -11.4 3.7e-30 0.99 0.00 1.00 FALSE
5 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -11.4 -9.2 2.5e-20 0.86 0.02 0.98 FALSE
6 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -7.1 -9.5 1.5e-21 0.87 0.02 0.91 FALSE
7 GTEx Colon Transverse GNA12 0.19 0.08 lasso 4 0.10 2.3e-05 5.7 -6.6 5.4e-11 0.58 0.27 0.71 FALSE
8 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -7.1 -9.6 7.9e-22 0.86 0.04 0.95 FALSE
9 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -11.3 -10.4 2.2e-25 0.87 0.01 0.99 FALSE
10 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -11.4 -11.0 2.5e-28 0.94 0.01 0.99 FALSE
11 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 -11.2 -9.2 2.3e-20 0.78 0.01 0.99 FALSE
12 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 -7.2 -9.3 8.6e-21 0.86 0.79 0.21 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic GNA12 0.10 0.15 lasso 3 0.12 4.2e-07 5.3 -6.0 2.4e-09 0.54 0.32 0.67 FALSE
14 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 -6.9 -9.2 2.7e-20 0.87 0.13 0.87 FALSE
15 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 -7.0 -7.7 1.4e-14 0.72 0.06 0.80 FALSE
16 GTEx Stomach GNA12 0.18 0.16 lasso 2 0.13 6.6e-07 -7.1 -7.2 5.7e-13 0.70 0.32 0.68 FALSE
17 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -11.0 -11.2 6.9e-29 0.94 0.02 0.91 FALSE
18 METSIM Adipose GNA12 0.07 0.05 lasso 3 0.05 3.3e-08 -7.0 -7.1 1.1e-12 0.72 0.28 0.72 FALSE
19 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -8.3 -7.9 3.3e-15 0.63 0.91 0.09 FALSE
20 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -11.4 11.6 3.2e-31 -0.90 0.01 0.99 TRUE
21 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 5.3 -7.1 1.2e-12 0.52 1.00 0.00 FALSE
22 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 7.1 -9.9 6.0e-23 0.71 0.01 0.69 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNA12 0.03 0.04 lasso 1 0.04 3.0e-05 -7.1 -7.1 1.1e-12 0.72 0.07 0.78 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 7.1 8.2 3.0e-16 -0.60 0.03 0.92 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 4.7 -9.4 6.2e-21 0.78 0.06 0.74 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma AMZ1 0.08 0.01 blup 71 0.05 1.3e-05 -7.1 5.3 1.0e-07 -0.60 0.04 0.80 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma AMZ1 0.32 0.04 enet 19 0.20 3.3e-19 -8.3 5.2 2.1e-07 -0.52 0.16 0.84 FALSE