Best TWAS P=3.45e-09 · Best GWAS P=3.22e-10 conditioned to 0.0165
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | KCTD9 | 0.23 | -0.01 | lasso | 6 | 0.00 | 3.8e-01 | -5.3 | -5.4 | 6.6e-08 | 0.72 | 0.09 | 0.22 | FALSE |
| 2 | GTEx | Muscle Skeletal | KCTD9 | 0.11 | 0.07 | lasso | 5 | 0.06 | 7.9e-07 | -5.5 | -5.9 | 3.4e-09 | 0.85 | 0.12 | 0.87 | TRUE |
| 3 | YFS | Blood | KCTD9 | 0.04 | 0.04 | lasso | 8 | 0.04 | 7.8e-12 | -5.3 | 5.4 | 7.7e-08 | -0.73 | 0.73 | 0.27 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | KCTD9 | 0.03 | 0.01 | blup | 75 | 0.01 | 1.1e-02 | -5.9 | -5.9 | 4.9e-09 | 0.88 | 0.02 | 0.69 | FALSE |