Best TWAS P=5.26e-13 · Best GWAS P=1.79e-12 conditioned to 0.356
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | KIAA1429 | 0.10 | 0.10 | lasso | 8 | 0.09 | 1.8e-11 | -7.0 | 7.0 | 3.5e-12 | -1.00 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | KIAA1429 | 0.16 | 0.13 | lasso | 2 | 0.11 | 9.5e-09 | -7.0 | 7.0 | 2.2e-12 | -1.00 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Testis | KIAA1429 | 0.29 | 0.22 | enet | 21 | 0.22 | 3.3e-10 | -7.0 | 7.2 | 5.3e-13 | -0.93 | 0.01 | 0.99 | TRUE |
| 4 | METSIM | Adipose | KIAA1429 | 0.04 | 0.03 | lasso | 7 | 0.03 | 1.8e-05 | -7.0 | 7.1 | 1.7e-12 | -1.00 | 0.01 | 0.99 | FALSE |
| 5 | METSIM | Adipose | RP11-267M23.4 | 0.04 | 0.04 | lasso | 2 | 0.02 | 1.1e-04 | -7.0 | -7.0 | 2.0e-12 | 0.99 | 0.01 | 0.99 | FALSE |
| 6 | NTR | Blood | RAD54B | 0.03 | 0.02 | lasso | 3 | 0.02 | 3.7e-06 | -5.6 | -5.7 | 1.5e-08 | 0.76 | 0.39 | 0.60 | FALSE |
| 7 | ROSMAP | Brain Pre-frontal Cortex | RP11-267M23.4 | 0.08 | 0.04 | bslmm | 446 | 0.03 | 2.4e-05 | -7.0 | -5.8 | 5.4e-09 | 0.87 | 0.01 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | KIAA1429 | 0.13 | 0.08 | blup | 57 | 0.07 | 3.5e-04 | -5.0 | 5.8 | 7.7e-09 | -0.77 | 0.04 | 0.63 | FALSE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA1429 | 0.10 | 0.05 | blup | 57 | 0.08 | 4.1e-08 | -7.0 | 6.3 | 2.8e-10 | -0.84 | 0.01 | 0.99 | FALSE |