Best TWAS P=4.96e-11 · Best GWAS P=7.22e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | IPPK | 0.17 | 0.07 | enet | 8 | 0.07 | 2.7e-06 | -6.0 | 5.4 | 5.9e-08 | 0.03 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Testis | NFIL3 | 0.47 | 0.33 | enet | 8 | 0.29 | 3.8e-13 | -6.5 | 6.6 | 5.0e-11 | -0.99 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ECM2 | 0.10 | 0.04 | lasso | 2 | 0.04 | 4.2e-05 | -5.4 | -5.3 | 1.1e-07 | -0.03 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | IPPK | 0.03 | 0.04 | blup | 50 | 0.04 | 6.7e-05 | -5.5 | 5.5 | 3.1e-08 | 0.03 | 0.01 | 0.98 | TRUE |