[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr10:123,438,113-124,889,817

Best TWAS P=6.42e-12 · Best GWAS P=1.87e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 6.4 -6.5 8.7e-11 0.76 0.16 0.78 FALSE
2 GTEx Muscle Skeletal PLEKHA1 0.10 0.04 lasso 3 0.04 8.2e-05 -6.9 -5.6 2.1e-08 0.86 0.02 0.98 FALSE
3 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 6.4 -5.7 9.6e-09 0.64 0.25 0.75 FALSE
4 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -5.3 -6.0 1.6e-09 0.81 0.02 0.97 FALSE
5 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 6.4 -6.8 9.2e-12 0.80 0.08 0.92 FALSE
6 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -6.9 -6.9 6.4e-12 0.99 0.01 0.99 TRUE
7 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 6.4 -6.4 2.0e-10 0.77 0.11 0.86 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARMS2 0.23 0.20 lasso 2 0.21 7.0e-09 -5.4 -5.7 1.3e-08 0.65 0.84 0.11 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 6.4 -5.7 1.2e-08 0.83 0.02 0.80 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -6.9 -6.6 3.1e-11 0.81 0.00 1.00 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 6.3 -6.3 2.5e-10 0.77 0.28 0.72 FALSE