Best TWAS P=1.66e-09 · Best GWAS P=2.7e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | TMEM121 | 0.11 | 0.10 | lasso | 5 | 0.08 | 4.9e-06 | 5.2 | 5.2 | 1.8e-07 | 0.93 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Whole Blood | TMEM121 | 0.08 | 0.10 | lasso | 3 | 0.09 | 1.8e-08 | 5.9 | -6.0 | 1.7e-09 | -0.97 | 0.01 | 0.99 | TRUE |
| 3 | METSIM | Adipose | TMEM121 | 0.04 | 0.02 | bslmm | 122 | 0.01 | 2.6e-03 | 5.9 | -6.0 | 2.1e-09 | -0.86 | 0.01 | 0.98 | FALSE |