Best TWAS P=8.49e-11 · Best GWAS P=9.48e-11 conditioned to 0.364
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | MARK3 | 0.11 | 0.03 | lasso | 4 | 0.04 | 1.5e-03 | 6.5 | 6.5 | 8.5e-11 | 0.91 | 0.04 | 0.84 | TRUE |
| 2 | GTEx | Thyroid | TRMT61A | 0.11 | 0.03 | lasso | 4 | 0.02 | 1.2e-02 | 6.4 | -6.1 | 1.0e-09 | -0.95 | 0.01 | 0.98 | FALSE |
| 3 | METSIM | Adipose | TRAF3 | 0.04 | 0.02 | enet | 7 | 0.04 | 4.5e-06 | 5.0 | 5.3 | 1.0e-07 | 0.03 | 0.05 | 0.94 | TRUE |
| 4 | YFS | Blood | MARK3 | 0.04 | 0.04 | lasso | 3 | 0.04 | 1.6e-12 | 6.3 | 6.2 | 4.8e-10 | 0.87 | 0.03 | 0.97 | FALSE |