[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr16:71,070,698-72,569,466

Best TWAS P=1.76e-09 · Best GWAS P=1.26e-10 conditioned to 0.000106

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PHLPP2 0.04 0.01 bslmm 456 0.02 4.7e-04 -4.5 -5.6 2.2e-08 0.57 0.39 0.53 FALSE
2 GTEx Heart Left Ventricle PHLPP2 0.14 0.10 lasso 8 0.07 1.8e-04 5.1 5.2 1.7e-07 -0.24 0.30 0.58 FALSE
3 GTEx Skin Sun Exposed Lower leg AP1G1 0.06 0.00 enet 15 0.01 5.7e-02 -4.8 -5.2 1.8e-07 0.54 0.17 0.62 FALSE
4 GTEx Spleen PHLPP2 0.18 0.11 lasso 13 0.09 2.2e-03 5.2 5.3 1.2e-07 -0.27 0.14 0.25 FALSE
5 GTEx Testis PHLPP2 0.29 0.38 enet 20 0.37 3.0e-17 -5.5 5.2 2.3e-07 -0.64 0.11 0.89 FALSE
6 METSIM Adipose PHLPP2 0.07 0.03 lasso 5 0.06 1.7e-09 4.8 6.0 1.8e-09 -0.46 0.75 0.25 FALSE
7 YFS Blood ATXN1L 0.02 0.02 blup 413 0.02 6.5e-07 4.3 5.8 7.7e-09 -0.45 0.91 0.08 FALSE
8 YFS Blood PHLPP2 0.04 0.03 bslmm 459 0.05 5.5e-16 -5.3 6.0 1.8e-09 -0.52 0.41 0.59 TRUE
9 The Cancer Genome Atlas Prostate Adenocarcinoma AP1G1 0.11 0.02 enet 27 0.04 1.2e-04 4.8 -5.9 3.8e-09 0.28 0.04 0.58 FALSE
10 The Cancer Genome Atlas Testicular Germ Cell Tumors PHLPP2 0.11 0.03 lasso 6 0.01 1.2e-01 4.8 5.9 3.4e-09 -0.43 0.03 0.48 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma MARVELD3 0.08 0.01 blup 44 0.06 7.1e-07 -5.4 5.8 5.1e-09 -0.49 0.03 0.95 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma PHLPP2 0.20 0.08 blup 67 0.14 1.4e-13 5.1 5.3 1.4e-07 -0.32 0.11 0.89 FALSE