[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr2:206,284,251-209,182,548

Best TWAS P=3.02e-10 · Best GWAS P=4.1e-09 conditioned to 0.00186

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous METTL21A 0.10 0.02 lasso 4 0.02 1.6e-02 -4.8 5.5 4.6e-08 0.32 0.16 0.34 FALSE
2 GTEx Brain Putamen basal ganglia NDUFS1 0.16 0.06 enet 6 0.05 2.9e-02 -4.5 5.3 1.4e-07 0.03 0.04 0.68 FALSE
3 GTEx Cells Transformed fibroblasts CREB1 0.15 0.00 enet 7 0.00 2.8e-01 -4.9 -6.3 3.0e-10 -0.50 0.10 0.56 TRUE
4 GTEx Colon Sigmoid AC007383.4 0.15 0.14 enet 13 0.09 3.8e-04 -4.8 5.2 1.8e-07 0.02 0.02 0.96 FALSE
5 GTEx Esophagus Gastroesophageal Junction NDUFS1 0.16 0.09 enet 22 0.03 2.4e-02 -4.8 5.5 4.0e-08 0.01 0.02 0.94 TRUE
6 GTEx Esophagus Mucosa METTL21A 0.10 0.10 enet 9 0.12 1.8e-08 -4.8 5.3 9.7e-08 0.57 0.27 0.72 FALSE
7 GTEx Esophagus Muscularis NDUFS1 0.17 0.19 enet 21 0.18 5.1e-11 -4.8 5.1 2.8e-07 -0.02 0.02 0.97 FALSE
8 GTEx Heart Atrial Appendage AC007383.4 0.12 0.10 enet 21 0.09 9.8e-05 -4.9 5.1 2.8e-07 0.00 0.03 0.97 FALSE
9 GTEx Heart Left Ventricle AC007383.4 0.17 0.13 enet 19 0.16 9.7e-09 -4.8 5.1 2.9e-07 0.00 0.02 0.97 FALSE
10 GTEx Nerve Tibial AC007383.4 0.14 0.06 lasso 6 0.05 3.0e-04 -4.9 5.3 1.3e-07 0.01 0.02 0.97 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma CREB1 0.03 0.01 blup 64 0.01 2.5e-02 -5.2 -5.4 6.8e-08 -0.49 0.09 0.53 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma FAM119A 0.04 0.02 blup 51 0.03 1.0e-06 -4.6 5.4 8.1e-08 0.64 0.03 0.96 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CREB1 0.11 0.02 enet 7 0.02 1.7e-03 4.5 -5.3 1.4e-07 -0.70 0.01 0.85 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma FAM119A 0.09 0.12 lasso 2 0.12 4.4e-12 -4.8 5.3 1.2e-07 0.50 0.02 0.97 FALSE