[Hub]/) : Traits : Arm predicted mass (right) :

chr3:55,894,951-57,412,804

Best TWAS P=3.07e-13 · Best GWAS P=1.4e-09 conditioned to 0.677

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts FAM208A 0.10 0.00 lasso 4 0.00 1.3e-01 -6.0 5.7 1.1e-08 -0.94 0.01 0.97 FALSE
2 YFS Blood CCDC66 0.11 0.09 lasso 8 0.11 6.0e-34 -5.4 -5.4 7.5e-08 0.50 0.24 0.76 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC66 0.09 0.03 lasso 8 0.05 4.2e-11 -4.9 -6.7 2.4e-11 0.65 0.16 0.84 FALSE
4 The Cancer Genome Atlas Glioblastoma Multiforme CCDC66 0.19 0.02 enet 14 0.12 1.7e-04 2.8 -5.4 5.5e-08 0.24 0.04 0.19 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC66 0.05 0.05 blup 56 0.06 1.0e-07 -6.0 -7.1 1.6e-12 0.81 0.00 1.00 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf63 0.03 0.01 enet 4 0.01 1.3e-02 -6.0 5.4 7.4e-08 -0.93 0.01 0.89 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC66 0.09 0.05 blup 56 0.06 5.3e-07 -5.4 -5.1 2.9e-07 0.60 0.13 0.87 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC66 0.16 0.13 enet 12 0.16 3.1e-17 -5.4 -5.6 2.6e-08 0.29 0.12 0.88 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma CCDC66 0.05 0.06 blup 56 0.05 9.7e-07 -6.1 -7.3 3.1e-13 0.80 0.00 1.00 TRUE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CCDC66 0.03 0.03 blup 56 0.03 9.6e-05 -4.8 -6.1 1.3e-09 0.57 0.12 0.73 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC66 0.08 0.01 blup 56 0.07 7.2e-04 -5.4 -5.7 1.5e-08 0.36 0.07 0.42 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC66 0.15 0.10 enet 11 0.13 7.3e-14 -4.8 -5.7 1.0e-08 0.39 0.21 0.79 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC66 0.05 0.01 blup 57 0.02 8.4e-03 -4.9 -6.1 8.3e-10 0.64 0.06 0.62 FALSE