[Hub]/) : Traits : Arm predicted mass (right) :

chr3:51,860,817-53,860,103

Best TWAS P=1.9e-09 · Best GWAS P=1.05e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NT5DC2 0.11 0.05 enet 22 0.04 5.0e-06 3.4 -5.1 3.0e-07 -0.47 0.27 0.66 FALSE
2 GTEx Pancreas RFT1 0.32 0.13 lasso 4 0.17 1.3e-07 5.7 5.2 1.9e-07 0.93 0.00 1.00 FALSE
3 GTEx Prostate RFT1 0.39 0.18 enet 17 0.24 1.1e-06 3.6 5.7 1.4e-08 0.68 0.10 0.83 FALSE
4 GTEx Stomach RFT1 0.23 0.03 enet 19 0.06 6.3e-04 3.6 5.6 1.8e-08 0.75 0.07 0.86 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma RFT1 0.18 0.10 lasso 7 0.10 1.8e-08 5.2 5.4 7.8e-08 0.97 0.00 1.00 TRUE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMEM110 0.19 0.13 blup 59 0.13 4.2e-11 4.6 5.4 7.4e-08 0.84 0.06 0.94 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma RFT1 0.10 0.08 enet 11 0.15 2.3e-29 5.0 5.4 5.7e-08 0.80 0.03 0.96 TRUE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RFT1 0.14 0.08 enet 12 0.15 5.5e-08 5.2 5.4 8.2e-08 0.78 0.01 0.98 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma RFT1 0.10 0.05 enet 12 0.05 1.0e-03 5.3 5.5 4.0e-08 0.87 0.01 0.93 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM110 0.27 0.10 blup 59 0.14 3.0e-15 4.5 5.2 2.4e-07 0.84 0.01 0.99 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma RFT1 0.24 0.12 lasso 5 0.20 1.3e-11 5.0 5.2 1.7e-07 0.81 0.02 0.97 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma NISCH 0.06 0.05 lasso 4 0.04 7.5e-06 5.2 5.1 3.0e-07 0.54 0.00 1.00 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma SPCS1 0.15 0.03 lasso 3 0.04 4.3e-05 4.9 5.4 6.4e-08 0.58 0.00 0.78 TRUE
14 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM110 0.13 0.06 blup 59 0.08 3.3e-09 3.3 5.2 1.6e-07 0.67 0.70 0.25 TRUE
15 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RFT1 0.31 0.07 blup 45 0.19 1.8e-09 3.2 6.0 2.1e-09 0.86 0.02 0.98 FALSE
16 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SFMBT1 0.17 0.08 lasso 2 0.06 5.5e-04 5.3 5.3 1.2e-07 0.97 0.01 0.94 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma RFT1 0.14 0.11 blup 45 0.11 1.9e-12 5.0 5.4 6.0e-08 0.92 0.01 0.99 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma SPCS1 0.11 0.00 blup 41 0.01 9.9e-03 -3.6 5.9 3.5e-09 0.36 0.00 0.09 TRUE
19 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RFT1 0.07 0.03 enet 7 0.06 1.2e-07 4.7 5.5 3.0e-08 0.75 0.02 0.98 FALSE
20 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RFT1 0.21 0.10 lasso 6 0.23 1.9e-15 5.2 5.3 9.6e-08 0.82 0.01 0.99 FALSE
21 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMEM110 0.20 0.13 blup 59 0.15 3.0e-10 5.6 5.5 3.2e-08 0.82 0.00 1.00 TRUE
22 The Cancer Genome Atlas Prostate Adenocarcinoma RFT1 0.18 0.09 blup 45 0.09 4.8e-10 5.2 5.2 1.7e-07 0.93 0.01 0.99 TRUE
23 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM110 0.20 0.06 blup 59 0.10 1.2e-10 5.6 5.5 5.0e-08 0.83 0.00 1.00 FALSE
24 The Cancer Genome Atlas Soft Tissue Sarcoma RFT1 0.16 0.12 enet 16 0.14 1.7e-08 5.2 5.4 5.2e-08 0.90 0.01 0.99 FALSE
25 The Cancer Genome Atlas Soft Tissue Sarcoma TMEM110 0.12 0.07 blup 59 0.12 7.5e-08 5.4 5.3 1.4e-07 0.73 0.02 0.98 FALSE
26 The Cancer Genome Atlas Skin Cutaneous Melanoma RFT1 0.29 0.04 blup 45 0.11 8.2e-04 5.0 5.8 7.8e-09 0.79 0.01 0.83 FALSE
27 The Cancer Genome Atlas Stomach Adenocarcinoma RFT1 0.13 0.05 blup 45 0.10 6.9e-08 5.3 6.0 2.8e-09 0.85 0.01 0.99 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma TMEM110 0.19 0.12 blup 59 0.13 1.6e-09 4.7 5.2 2.6e-07 0.79 0.14 0.85 FALSE
29 The Cancer Genome Atlas Testicular Germ Cell Tumors RFT1 0.39 0.22 lasso 4 0.25 3.1e-09 5.0 5.3 1.3e-07 0.94 0.01 0.99 FALSE
30 The Cancer Genome Atlas Testicular Germ Cell Tumors TMEM110 0.20 0.01 lasso 2 0.09 3.2e-04 5.6 5.6 2.7e-08 0.97 0.00 0.90 FALSE
31 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RFT1 0.29 0.15 blup 45 0.15 6.5e-05 4.7 6.0 1.9e-09 0.85 0.01 0.85 TRUE