Best TWAS P=2.05e-11 · Best GWAS P=1.51e-09 conditioned to 0.0302
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | DCBLD2 | 0.16 | 0.13 | lasso | 3 | 0.14 | 2.4e-11 | -5.8 | 5.4 | 8.1e-08 | 0.64 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | DCBLD2 | 0.32 | 0.22 | lasso | 7 | 0.22 | 1.6e-06 | -4.2 | 5.2 | 1.9e-07 | 0.59 | 0.05 | 0.94 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | DCBLD2 | 0.24 | 0.21 | lasso | 4 | 0.19 | 1.4e-07 | -5.3 | 5.2 | 1.7e-07 | 0.69 | 0.03 | 0.97 | FALSE |
| 4 | GTEx | Nerve Tibial | DCBLD2 | 0.14 | 0.05 | lasso | 5 | 0.03 | 1.7e-03 | 4.4 | 5.5 | 3.5e-08 | 0.33 | 0.16 | 0.44 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | ST3GAL6 | 0.07 | 0.04 | enet | 16 | 0.04 | 2.0e-04 | 4.6 | 5.5 | 4.3e-08 | 0.83 | 0.04 | 0.95 | FALSE |
| 6 | GTEx | Thyroid | DCBLD2 | 0.14 | 0.12 | lasso | 5 | 0.15 | 1.5e-11 | -5.8 | 6.2 | 5.1e-10 | 0.74 | 0.02 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | DCBLD2 | 0.07 | 0.06 | enet | 3 | 0.07 | 7.6e-04 | -5.2 | 5.4 | 7.0e-08 | 0.60 | 0.02 | 0.84 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DCBLD2 | 0.09 | 0.01 | enet | 16 | 0.04 | 9.6e-05 | 4.6 | 6.7 | 2.1e-11 | 0.66 | 0.03 | 0.88 | TRUE |