Best TWAS P=5.36e-67 · Best GWAS P=6.57e-68 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 17.4 | 17.3 | 5.4e-67 | 0.98 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Colon Transverse | ACPL2 | 0.15 | -0.01 | lasso | 4 | 0.00 | 5.7e-01 | 6.2 | 6.3 | 3.2e-10 | 0.30 | 0.05 | 0.05 | TRUE |
| 3 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | 10.6 | 11.8 | 5.4e-32 | 0.60 | 0.24 | 0.61 | FALSE |
| 4 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | 10.1 | 12.3 | 1.0e-34 | 0.62 | 0.07 | 0.92 | FALSE |
| 5 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 17.3 | 14.8 | 1.9e-49 | 0.88 | 0.01 | 0.99 | TRUE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 11.0 | 12.9 | 4.2e-38 | 0.59 | 0.04 | 0.43 | FALSE |