[Hub]/) : Traits : Arm predicted mass (right) :

chr3:153,142,317-154,733,231

Best TWAS P=1.96e-11 · Best GWAS P=4.03e-10 conditioned to 0.123

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX36 0.05 0.06 blup 357 0.05 1.3e-06 -5.1 -6.1 1.2e-09 -0.48 0.84 0.16 FALSE
2 GTEx Adipose Subcutaneous ARHGEF26 0.10 0.06 enet 8 0.07 2.2e-06 -5.1 5.2 1.5e-07 0.36 0.79 0.20 FALSE
3 GTEx Ovary ARHGEF26 0.14 0.03 enet 15 0.06 1.4e-02 6.1 6.7 2.0e-11 0.79 0.05 0.63 TRUE
4 GTEx Pancreas ARHGEF26 0.26 0.26 lasso 5 0.28 3.2e-12 -5.0 5.9 3.0e-09 0.44 0.78 0.22 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic ARHGEF26 0.13 0.11 lasso 4 0.07 6.8e-05 -5.0 5.4 7.5e-08 0.40 0.69 0.28 FALSE
6 GTEx Spleen DHX36 0.39 0.09 enet 21 0.34 2.1e-09 -3.4 -5.6 2.5e-08 -0.67 0.14 0.85 FALSE
7 GTEx Thyroid ARHGEF26 0.09 0.07 enet 17 0.08 1.9e-06 -5.2 6.2 6.5e-10 0.42 0.68 0.27 FALSE
8 METSIM Adipose ARHGEF26 0.07 0.08 lasso 6 0.07 3.5e-11 -5.1 5.3 1.4e-07 0.43 0.87 0.13 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGEF 0.04 0.04 enet 12 0.04 1.1e-05 -4.8 5.9 3.4e-09 0.48 0.27 0.63 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma DHX36 0.11 0.09 enet 11 0.10 6.4e-12 -4.7 -5.6 2.6e-08 -0.57 0.97 0.03 FALSE
11 The Cancer Genome Atlas Soft Tissue Sarcoma DHX36 0.05 0.00 enet 9 0.01 1.0e-01 -4.0 -5.1 2.9e-07 -0.78 0.01 0.61 FALSE