Best TWAS P=1.01e-13 · Best GWAS P=3.15e-17 conditioned to 4.93e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | WDR70 | 0.06 | 0.03 | lasso | 8 | 0.03 | 0.00346 | -5.8 | 6.3 | 3.7e-10 | -0.72 | 0.39 | 0.41 | FALSE |
| 2 | GTEx | Whole Blood | NUP155 | 0.05 | 0.01 | enet | 14 | 0.04 | 0.00011 | -8.4 | 5.2 | 2.6e-07 | -0.61 | 0.01 | 0.94 | FALSE |
| 3 | GTEx | Whole Blood | C5orf42 | 0.07 | 0.00 | enet | 16 | 0.01 | 0.01830 | -8.4 | 6.0 | 1.8e-09 | -0.68 | 0.01 | 0.88 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C5orf42 | 0.04 | 0.05 | lasso | 3 | 0.04 | 0.00108 | -7.7 | 7.4 | 1.0e-13 | -0.92 | 0.00 | 0.94 | TRUE |