Best TWAS P=1.71e-10 · Best GWAS P=2.07e-09 conditioned to 0.542
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | DAB2 | 0.20 | 0.20 | lasso | 14 | 0.21 | 3e-67 | 5.9 | -6.4 | 1.7e-10 | 0.90 | 0.02 | 0.98 | TRUE |
2 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | DAB2 | 0.18 | -0.01 | blup | 83 | 0.05 | 2e-02 | 1.3 | -5.2 | 2.5e-07 | 0.59 | 0.02 | 0.19 | FALSE |