Best TWAS P=9.83e-10 · Best GWAS P=1.79e-08 conditioned to 0.0115
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | THBS3 | 0.12 | 0.09 | enet | 8 | 0.09 | 3.6e-07 | 4.3 | -6.1 | 9.8e-10 | 0.59 | 0.04 | 0.95 | TRUE |
| 2 | GTEx | Thyroid | MUC1 | 0.11 | 0.02 | enet | 15 | 0.09 | 1.5e-07 | 4.1 | 5.9 | 3.3e-09 | -0.26 | 0.06 | 0.93 | FALSE |
| 3 | YFS | Blood | THBS3 | 0.29 | 0.22 | enet | 38 | 0.31 | 6.4e-105 | 4.1 | -5.3 | 1.1e-07 | 0.39 | 0.56 | 0.39 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | THBS3 | 0.04 | 0.01 | blup | 25 | 0.03 | 3.1e-04 | -5.3 | -5.8 | 5.1e-09 | 0.64 | 0.02 | 0.79 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | GBAP1 | 0.04 | 0.04 | blup | 26 | 0.04 | 2.5e-05 | -5.0 | 5.5 | 4.8e-08 | -0.45 | 0.04 | 0.92 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GBA | 0.05 | 0.01 | lasso | 2 | 0.01 | 2.3e-02 | -5.6 | 5.8 | 8.9e-09 | -0.93 | 0.00 | 0.86 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GBAP1 | 0.06 | 0.06 | lasso | 9 | 0.06 | 3.5e-07 | -5.0 | 5.8 | 6.9e-09 | -0.55 | 0.04 | 0.96 | FALSE |