Best TWAS P=1.17e-30 · Best GWAS P=2.41e-124 conditioned to 2.87e-65
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FTO | 0.11 | 0.00 | bslmm | 739 | 0.02 | 1.6e-03 | -2.02 | 10.4 | 1.9e-25 | 0.38 | 0.09 | 0.55 | TRUE |
| 2 | GTEx | Testis | AKTIP | 0.19 | 0.00 | enet | 26 | 0.00 | 1.9e-01 | 0.66 | 11.5 | 1.2e-30 | 0.51 | 0.03 | 0.40 | TRUE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | FTO | 0.27 | 0.16 | enet | 13 | 0.14 | 6.7e-05 | -1.90 | 9.1 | 8.8e-20 | 0.33 | 0.11 | 0.32 | TRUE |