[Hub]/) : Traits : Arm fat percentage (left) :

chr17:44,788,310-47,718,188

Best TWAS P=2.17e-12 · Best GWAS P=3.55e-16 conditioned to 0.698

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATP5G1 0.07 0.05 lasso 3 0.06 4.7e-08 -5.90 6.1 1.4e-09 -0.62 0.94 0.06 FALSE
2 CommonMind Brain Pre-frontal Cortex SNF8 0.08 0.07 lasso 5 0.08 9.3e-10 -5.46 7.0 2.2e-12 -0.84 0.08 0.92 TRUE
3 GTEx Artery Aorta SNF8 0.12 0.12 lasso 6 0.10 2.3e-06 -5.31 5.3 9.2e-08 -0.63 0.67 0.23 FALSE
4 GTEx Artery Aorta AC091133.1 0.10 0.07 lasso 5 0.07 1.2e-04 -5.31 5.6 2.3e-08 -0.65 0.29 0.49 FALSE
5 GTEx Artery Aorta RP11-6N17.9 0.23 0.12 enet 19 0.19 9.5e-11 -4.55 -5.1 2.7e-07 0.09 0.98 0.02 FALSE
6 GTEx Artery Aorta RP11-6N17.10 0.20 0.07 enet 24 0.14 3.5e-08 -4.55 -5.5 5.0e-08 0.11 0.46 0.17 FALSE
7 GTEx Brain Caudate basal ganglia RP11-6N17.9 0.45 -0.01 enet 28 0.16 3.3e-05 -0.68 -5.5 5.1e-08 0.09 0.06 0.14 FALSE
8 GTEx Brain Cerebellar Hemisphere CDK5RAP3 0.22 0.10 lasso 6 0.09 2.6e-03 4.56 -5.5 3.7e-08 0.09 0.08 0.41 FALSE
9 GTEx Brain Cerebellar Hemisphere RP11-6N17.10 0.21 0.16 lasso 5 0.13 3.8e-04 4.56 -5.2 2.0e-07 0.09 0.09 0.44 FALSE
10 GTEx Brain Cortex ARL17A 0.35 0.20 lasso 6 0.25 1.7e-07 4.93 5.9 3.2e-09 0.01 0.00 0.92 FALSE
11 GTEx Brain Nucleus accumbens basal ganglia CDK5RAP3 0.21 0.04 lasso 4 0.02 7.2e-02 5.44 -5.3 9.4e-08 0.08 0.08 0.39 FALSE
12 GTEx Cells Transformed fibroblasts SNF8 0.12 0.10 lasso 3 0.12 5.1e-09 -5.30 5.8 7.5e-09 -0.66 0.99 0.01 FALSE
13 GTEx Cells Transformed fibroblasts AC091133.1 0.14 0.07 enet 22 0.09 1.9e-07 -5.08 5.2 2.4e-07 -0.60 0.89 0.08 FALSE
14 GTEx Esophagus Gastroesophageal Junction CDK5RAP3 0.21 0.09 lasso 6 0.07 1.2e-03 -4.55 -5.4 6.8e-08 0.10 0.09 0.50 FALSE
15 GTEx Esophagus Gastroesophageal Junction RP11-6N17.9 0.18 0.14 lasso 3 0.09 4.9e-04 -4.55 -5.7 1.2e-08 0.12 0.03 0.73 FALSE
16 GTEx Esophagus Muscularis COPZ2 0.14 0.04 lasso 5 0.06 1.3e-04 3.79 5.2 1.6e-07 -0.05 0.18 0.04 FALSE
17 GTEx Esophagus Muscularis SNF8 0.08 0.03 lasso 3 0.01 5.7e-02 -6.27 6.2 7.5e-10 -0.71 0.03 0.77 FALSE
18 GTEx Heart Atrial Appendage CDK5RAP3 0.13 0.00 enet 18 0.04 5.1e-03 1.11 -5.4 8.3e-08 0.10 0.09 0.05 FALSE
19 GTEx Heart Atrial Appendage ATP5G1 0.22 0.10 enet 6 0.13 1.3e-06 -5.30 5.3 1.2e-07 -0.62 0.95 0.01 TRUE
20 GTEx Heart Left Ventricle ATP5G1 0.24 0.22 lasso 4 0.22 9.3e-12 -5.81 6.3 2.6e-10 -0.64 1.00 0.00 FALSE
21 GTEx Liver ARL17A 0.34 0.18 lasso 9 0.18 9.8e-06 4.93 6.0 2.3e-09 0.04 0.00 0.86 TRUE
22 GTEx Muscle Skeletal ATP5G1 0.13 0.08 enet 18 0.07 5.1e-07 -5.08 5.2 1.5e-07 -0.67 0.92 0.08 FALSE
23 GTEx Muscle Skeletal UBE2Z 0.06 0.02 lasso 8 0.03 9.8e-04 -5.81 5.8 6.8e-09 -0.66 0.42 0.46 FALSE
24 GTEx Muscle Skeletal AC003665.1 0.05 0.03 enet 8 0.03 1.4e-03 4.82 6.1 9.7e-10 -0.11 0.12 0.73 FALSE
25 GTEx Nerve Tibial CDK5RAP3 0.41 0.35 enet 23 0.36 6.1e-27 -4.55 -5.4 7.5e-08 0.12 0.98 0.02 FALSE
26 GTEx Nerve Tibial UBE2Z 0.12 0.04 enet 16 0.05 1.5e-04 -5.31 5.4 5.2e-08 -0.60 0.89 0.01 FALSE
27 GTEx Nerve Tibial RP11-6N17.10 0.28 0.19 lasso 8 0.19 1.6e-13 -4.55 -5.3 1.1e-07 0.12 0.98 0.02 FALSE
28 GTEx Ovary ATP5G1 0.15 0.08 enet 13 0.09 2.8e-03 -4.88 6.1 9.6e-10 -0.66 0.06 0.72 FALSE
29 GTEx Pancreas CDK5RAP3 0.11 -0.01 lasso 4 0.02 5.1e-02 4.56 -6.2 7.2e-10 0.04 0.09 0.18 FALSE
30 GTEx Pancreas RP11-6N17.9 0.15 0.04 lasso 5 0.04 9.3e-03 -2.56 -5.8 5.5e-09 0.07 0.13 0.17 FALSE
31 GTEx Skin Not Sun Exposed Suprapubic UBE2Z 0.11 0.07 lasso 6 0.04 1.8e-03 -6.27 6.3 2.8e-10 -0.68 0.10 0.12 FALSE
32 GTEx Skin Sun Exposed Lower leg UBE2Z 0.14 0.11 lasso 9 0.14 6.3e-12 -4.94 5.8 9.1e-09 -0.64 1.00 0.00 FALSE
33 GTEx Stomach RP11-6N17.9 0.13 0.02 lasso 6 0.04 8.0e-03 4.87 -5.6 2.1e-08 0.06 0.11 0.69 FALSE
34 GTEx Testis SNF8 0.23 0.11 lasso 5 0.08 1.6e-04 -5.31 5.3 1.4e-07 -0.62 0.68 0.08 FALSE
35 GTEx Testis RP11-6N17.4 0.14 0.02 lasso 10 0.02 4.8e-02 5.51 5.6 2.6e-08 -0.07 0.15 0.70 FALSE
36 GTEx Thyroid CDK5RAP3 0.21 0.14 lasso 5 0.18 1.6e-13 -4.55 -5.7 1.6e-08 0.13 0.98 0.02 FALSE
37 GTEx Thyroid SNF8 0.11 0.08 lasso 3 0.07 2.5e-06 -5.08 5.5 4.8e-08 -0.61 0.89 0.08 FALSE
38 GTEx Thyroid RP11-6N17.9 0.22 0.14 lasso 5 0.14 5.2e-11 -4.55 -5.5 3.1e-08 0.12 0.98 0.02 FALSE
39 GTEx Thyroid RP11-6N17.10 0.19 0.12 lasso 5 0.13 3.0e-10 -4.55 -5.9 4.2e-09 0.13 0.98 0.02 FALSE
40 The Cancer Genome Atlas Brain Lower Grade Glioma ATP5G1 0.08 0.02 enet 7 0.02 3.1e-03 -5.75 5.2 1.5e-07 -0.59 0.02 0.79 FALSE
41 The Cancer Genome Atlas Brain Lower Grade Glioma SNF8 0.11 0.12 lasso 4 0.12 1.4e-13 -5.48 5.6 1.7e-08 -0.65 0.38 0.62 FALSE
42 The Cancer Genome Atlas Prostate Adenocarcinoma CBX1 0.03 0.04 lasso 4 0.04 3.7e-05 5.55 -5.4 7.3e-08 0.07 0.01 0.99 FALSE
43 The Cancer Genome Atlas Prostate Adenocarcinoma CDK5RAP3 0.06 0.00 blup 62 0.03 1.0e-03 -3.93 -6.8 7.7e-12 0.07 0.01 0.44 TRUE
44 The Cancer Genome Atlas Prostate Adenocarcinoma SNF8 0.05 0.06 blup 47 0.06 1.0e-06 -6.27 5.4 7.7e-08 -0.64 0.04 0.96 FALSE
45 The Cancer Genome Atlas Thyroid Carcinoma SNF8 0.16 0.18 lasso 7 0.18 5.9e-17 -5.31 5.4 8.0e-08 -0.64 0.34 0.66 FALSE
46 The Cancer Genome Atlas Thyroid Carcinoma UBE2Z 0.13 0.09 lasso 4 0.12 2.7e-11 -5.31 5.9 4.8e-09 -0.64 0.04 0.96 FALSE