TWAS hub - CBX1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.0533	0.0224	2.2e-03	0.057	NA	0.027	NA	0.044	2.9e-05	NA	3.1e-03	NA	2.2e-04
2	GTEx	Cells Transformed fibroblasts	0.1810	0.0550	1.9e-07	0.049	NA	0.094	NA	0.097	1.3e-04	NA	1.6e-07	NA	1.0e-07
3	GTEx	Muscle Skeletal	0.0556	0.0266	5.1e-03	0.062	NA	0.034	NA	0.048	1.0e-06	NA	2.7e-04	NA	1.6e-05
4	METSIM	Adipose	0.0641	0.0274	1.7e-04	0.007	0.021	0.004	0.018	0.004	2.7e-02	0.00038	8.4e-02	0.00074	7.9e-02
5	TCGA	Breast Invasive Carcinoma	0.0221	0.0123	1.7e-03	-0.001	0.007	0.000	NA	-0.001	9.4e-01	0.00970	2.8e-01	NA	5.1e-01
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0295	0.0185	7.4e-03	0.013	0.013	0.010	NA	0.014	1.0e-02	0.01100	2.3e-02	NA	8.7e-03
7	TCGA	Brain Lower Grade Glioma	0.0521	0.0243	4.6e-05	0.010	0.026	0.019	NA	0.009	2.4e-02	0.00053	3.0e-03	NA	2.8e-02
8	TCGA	Prostate Adenocarcinoma	0.0343	0.0172	6.8e-04	0.043	0.023	0.040	NA	0.041	2.5e-05	0.00180	4.8e-05	NA	3.7e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Mouth/teeth dental problems: Dentures	8.7	14.7	23.6	-4.8	-4.9	-4.9	1.4	-2.5	-3.9	-3.7	-3.3
Systolic Blood Pressure	7.0	35.2	57.3	6.1	7.6	6.5	-0.2	4.2	6.9	4.9	7.5
Diabetes (mother)	6.3	8.1	23.3	4.8	2.5	2.1	-0.4	3.0	2.5	3.3	2.0
Systolic blood pressure, automated reading	6.0	17.6	30.2	5.0	5.5	4.1	0.3	3.1	4.7	3.8	4.8
Number of live births	5.9	8.3	14.3	-2.6	-2.9	-2.3	-0.2	-3.0	-3.5	-3.2	-3.8
Fasting Glucose	5.1	6.1	11.9	2.6	2.6	3.5	0.3	2.2	3.0	2.1	2.2
Illnesses of father: None of the above (group 1)	5.0	6.1	8.2	1.9	2.9	2.0	1.7	2.7	2.7	2.8	2.7
Ovarian Cancer	4.9	6.4	16.3	-2.2	-4.0	-1.5	2.5	0.5	-3.5	0.2	-3.0
Arm fat mass (right)	4.5	18.6	42.2	-2.9	-4.5	-4.0	0.6	-3.1	-6.1	-4.0	-6.5
Body Mass Index (BMI) (2010)	4.4	6.1	17.2	-0.6	-3.1	-1.3	-0.3	-1.0	-4.0	-1.6	-4.1
Weight	4.4	21.6	45.0	-3.9	-4.7	-3.8	-0.1	-3.8	-6.2	-4.8	-6.7
Trunk fat mass	4.3	18.5	39.7	-3.3	-4.3	-3.5	0.1	-3.4	-5.7	-4.6	-6.3
Waist circumference	4.3	15.8	39.1	-2.2	-4.2	-3.6	1.6	-2.5	-5.7	-3.2	-6.2
Whole body fat mass	4.3	18.1	40.8	-3.1	-4.3	-3.7	0.3	-3.3	-5.8	-4.2	-6.4
BMI	4.2	24.1	59.3	-2.4	-5.1	-4.2	0.3	-3.5	-7.5	-4.1	-7.7
Arm fat mass (left)	4.2	17.4	40.1	-2.6	-4.3	-4.1	0.8	-2.9	-5.8	-3.7	-6.3
Handedness (chirality/laterality): Left-handed	4.1	4.9	9.1	2.8	2.3	1.8	0.1	3.0	1.8	2.5	2.2
Headache pain in last month	3.9	6.7	10.7	-3.0	-2.8	-3.3	0.4	-2.0	-2.9	-2.2	-2.9
Medication: Allopurinol	3.9	5.2	7.1	2.5	2.7	2.3	-0.0	2.5	2.5	2.4	2.3
Fractured/broken bones in last 5 years	3.9	5.1	7.5	-1.5	-2.2	-0.4	-2.5	-2.7	-2.6	-2.7	-2.2
Leg fat mass (left)	3.9	15.3	38.2	-2.3	-3.7	-3.7	0.6	-3.1	-5.4	-3.5	-6.2
Type 2 Diabetes (T2D) (2012)	3.8	4.4	6.9	2.6	2.2	2.0	-0.6	2.3	2.2	2.0	2.2
Gout (self-reported)	3.8	5.2	7.7	2.6	2.5	1.8	0.7	2.5	2.8	2.5	2.2
Medication for pain relief, constipation, heartburn	3.8	6.5	10.6	3.3	3.1	2.6	0.0	2.0	2.9	2.5	2.6
Leg fat mass (right)	3.8	14.7	36.3	-2.2	-3.6	-3.7	0.9	-3.0	-5.3	-3.5	-6.0
Mean Putamen Volume	3.6	4.1	6.0	-1.9	-2.4	-0.5	-2.5	-1.9	-2.2	-2.1	-2.0
Hip circumference	3.6	15.4	31.8	-3.4	-3.7	-3.7	-0.1	-3.1	-5.1	-4.0	-5.6
Ever had bowel cancer screening	3.4	4.0	8.1	-2.0	-0.8	-0.4	-2.4	-2.4	-1.9	-2.8	-1.9
Trunk fat percentage	3.3	13.4	28.7	-2.7	-3.7	-3.1	0.3	-2.8	-4.9	-4.0	-5.4
Arm fat percentage (right)	3.3	13.2	29.5	-1.8	-3.7	-3.9	0.7	-2.5	-5.2	-3.3	-5.4
High cholesterol (Self-reported)	3.3	5.8	19.6	0.4	1.3	1.2	4.4	2.9	1.4	2.9	2.2
Body fat percentage	3.2	12.8	29.6	-2.2	-3.4	-3.4	0.7	-2.8	-4.8	-3.6	-5.4
Basal metabolic rate	3.2	18.0	36.5	-3.9	-4.4	-3.2	-0.3	-3.4	-5.7	-4.2	-6.0
Arm fat-free mass (left)	3.2	16.3	34.8	-3.8	-4.0	-2.9	-0.1	-3.4	-5.5	-3.8	-5.9
Arm predicted mass (left)	3.2	16.4	34.8	-3.8	-4.1	-2.9	-0.4	-3.5	-5.5	-3.9	-5.9
Mouth/teeth dental problems	3.1	4.8	6.3	2.4	2.5	2.5	-0.8	2.3	2.1	2.5	1.9
Arm fat percentage (left)	3.1	12.4	28.9	-1.8	-3.6	-3.8	1.2	-2.2	-4.9	-3.0	-5.4
Body mass index (BMI)	3.0	12.9	34.6	-1.2	-3.5	-3.8	1.6	-2.1	-5.4	-2.3	-5.9
Leg fat percentage (right)	3.0	10.9	28.0	-1.3	-2.8	-3.5	1.4	-2.8	-4.4	-2.9	-5.3
Eye problems/disorders: Cataract	3.0	3.5	6.3	1.3	2.0	0.4	2.3	2.2	1.6	2.5	1.8
Deep venous thrombosis (DVT) (self-reported)	3.0	3.9	6.5	-2.5	-2.0	-1.6	-0.2	-2.2	-2.1	-2.1	-2.0
Leg predicted mass (left)	2.9	15.4	31.0	-3.7	-4.4	-2.9	0.1	-2.8	-5.5	-3.7	-5.6
Worrier / anxious feelings	2.9	5.5	8.4	2.1	1.7	2.9	2.4	2.8	1.7	2.7	2.0
Leg fat-free mass (left)	2.8	15.1	30.2	-3.6	-4.3	-2.9	0.0	-2.8	-5.4	-3.7	-5.5
Blood clot in the leg (DVT)	2.8	3.6	6.8	-2.6	-1.9	-1.5	-0.0	-2.1	-2.1	-2.0	-1.9
Whole body fat-free mass	2.8	16.0	31.5	-3.9	-4.2	-3.0	-0.4	-3.2	-5.4	-3.9	-5.6
Whole body water mass	2.8	15.8	31.5	-3.9	-4.2	-2.9	-0.3	-3.2	-5.4	-3.8	-5.6
Trunk predicted mass	2.7	15.3	28.2	-3.9	-3.9	-3.1	-0.9	-3.6	-5.0	-4.0	-5.3
Arm fat-free mass (right)	2.7	14.0	30.8	-3.6	-3.7	-2.7	0.1	-3.1	-5.0	-3.5	-5.5
Arm predicted mass (right)	2.7	13.7	30.8	-3.5	-3.7	-2.7	0.3	-3.0	-5.1	-3.3	-5.5
Leg fat percentage (left)	2.7	9.8	26.8	-1.0	-2.6	-3.4	0.9	-2.7	-4.2	-2.6	-5.2
Trunk fat-free mass	2.6	15.2	28.1	-3.9	-3.9	-3.0	-0.9	-3.5	-5.0	-4.0	-5.3
Maternal smoking around birth	2.5	3.6	7.3	-1.2	-1.1	-1.0	-2.1	-2.2	-1.9	-2.2	-2.7
Falls in the last year	2.5	3.3	6.1	-1.1	-1.9	-2.5	-0.9	-2.0	-1.6	-2.3	-1.7
Mouth/teeth dental problems: Loose teeth	2.5	2.9	5.9	-1.0	-0.7	-1.9	-1.8	-2.4	-1.3	-2.3	-1.5
Chronic bronchitis/emphysema (mother)	2.4	2.8	6.3	0.2	-0.9	-1.8	-2.0	-2.5	-1.2	-2.2	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.0	13.5	-3.7	-2.2	0.1	-0.7	-1.9	-2.5	-2.8	-1.8
Friendships satisfaction	2.4	3.0	7.1	1.3	1.4	0.9	0.6	1.8	2.3	1.8	2.7
Pain type(s) experienced in last month: Hip pain	2.4	3.0	8.9	-3.0	-1.9	-1.2	2.0	-1.2	-1.1	-1.5	-1.1
Bipolar Disorder (2011)	2.3	2.2	5.4	1.1	1.2	2.3	1.2	1.7	0.6	1.9	1.0
Type 2 Diabetes (T2D) (2018)	2.3	4.4	12.9	3.6	2.5	1.1	-0.2	1.3	2.4	1.8	1.9
Medication: Metformin	2.3	3.2	8.1	2.9	2.3	-0.5	0.7	1.5	2.0	1.9	1.3
Leg fat-free mass (right)	2.3	12.5	25.5	-3.4	-4.0	-2.5	-0.1	-2.3	-5.0	-3.2	-5.0
Leg predicted mass (right)	2.3	12.4	25.6	-3.3	-4.0	-2.5	0.0	-2.2	-5.0	-3.1	-5.1
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.7	4.5	-2.1	-1.3	-1.6	0.7	-1.4	-2.0	-1.6	-2.1
Lung cancer (father)	2.2	2.5	6.1	1.1	2.5	0.8	1.1	1.4	2.1	1.6	1.5
Exposure to tobacco smoke outside home	2.2	2.9	7.6	1.3	0.0	-2.6	2.8	1.6	0.1	2.1	-0.3
Shortness of breath walking on level ground	2.2	2.6	4.8	-2.2	-1.8	-1.2	-0.1	-1.6	-1.6	-1.8	-1.7
Diabetes diagnosed by doctor	2.2	3.6	8.0	2.8	2.5	-0.1	0.3	1.3	2.3	1.7	2.0
Irritability	2.2	3.7	6.0	2.0	2.3	0.9	1.8	2.0	1.8	2.4	1.8
Major Depression (MDD)	2.1	2.6	4.1	-1.1	-1.6	-0.2	-1.7	-1.6	-1.9	-2.0	-2.0
Osteoporosis (self-reported)	2.1	2.6	6.4	-2.5	-1.9	-1.4	-0.2	-1.0	-1.8	-1.8	-1.1
Stomach or abdominal pain in last month	2.0	2.5	6.1	-1.3	-1.6	-2.5	-0.2	-1.5	-1.1	-1.9	-1.4
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	4.2	1.6	1.6	-0.6	0.3	1.6	1.4	2.0	1.5
Diabetes (self-reported)	1.9	2.9	5.9	2.4	2.2	-0.2	1.0	1.1	2.0	1.7	1.7
Glaucoma (self-reported)	1.9	2.2	12.6	-0.1	0.7	0.9	3.6	1.1	0.9	1.1	0.8
Medication: Aspirin	1.9	2.4	6.3	-2.5	-1.5	-0.9	-0.8	-1.8	-1.5	-1.8	-0.8
Medication: Lisinopril	1.9	2.5	7.3	1.3	1.9	2.7	-0.2	0.2	1.9	0.8	1.8
Alcohol drinker status: Previous	1.9	2.1	5.1	-0.4	-1.5	-0.4	-1.9	-2.3	-0.6	-2.0	-1.1
Triglycerides	1.8	3.0	8.3	2.9	1.4	2.2	-1.2	1.7	1.0	1.8	0.8
Pulse rate	1.8	3.0	10.8	-3.3	-1.7	-1.4	0.8	-1.2	-1.6	-1.5	-1.1
Pulse wave Arterial Stiffness index	1.8	2.1	10.1	0.0	-1.4	-0.2	-3.2	-0.9	-1.2	-1.3	-0.6
Family relationship satisfaction	1.8	2.2	3.5	1.6	0.5	1.8	1.9	1.6	1.2	1.6	1.2
Risk taking	1.8	2.6	5.9	-0.6	-2.0	-1.0	-1.2	-1.3	-2.1	-1.5	-2.4
Ever had prostate specific antigen (PSA) test	1.8	2.1	4.6	-1.0	-1.4	-0.6	-2.2	-1.5	-1.2	-1.7	-1.4
Cholesterol lowering medication	1.8	2.7	9.0	0.6	1.1	1.0	3.0	1.7	1.2	1.8	1.5
Supplements: Calcium	1.8	1.9	3.5	0.7	1.2	1.7	0.9	1.9	1.5	1.4	1.5
Chronotype (morning person)	1.7	3.9	7.1	-2.3	-2.4	-2.1	2.7	-0.9	-1.8	-0.2	-2.1
Hand grip strength (left)	1.7	4.4	22.4	-2.3	-1.3	0.7	4.7	0.8	-1.7	0.8	-1.1
Chronic bronchitis/emphysema (father)	1.7	2.0	4.2	0.1	-1.3	-1.8	-2.1	-1.6	-0.3	-1.4	-1.4
Medication: Simvastatin	1.7	2.4	9.8	-1.1	0.2	-0.0	3.1	1.8	0.7	1.5	1.6
Medication: Cholesterol lowering	1.7	2.7	7.0	-0.2	1.0	-0.3	2.6	2.0	0.9	2.0	2.1
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	4.3	-1.2	-1.6	-1.9	-0.0	-1.2	-1.3	-1.2	-2.1
Eye problems/disorders: None of the above	1.7	2.0	7.4	-0.4	-0.9	-0.3	-2.7	-1.4	-1.2	-1.4	-1.4
Comparative height size at age 10	1.7	9.6	19.1	-4.4	-3.1	-1.5	-0.9	-2.4	-3.8	-3.7	-3.5
Basal cell carcinoma (self-reported)	1.7	2.0	4.2	-1.2	-2.0	-1.6	0.9	-1.0	-1.5	-0.9	-1.6
Crohns Disease (2017)	1.6	3.5	8.7	-0.2	1.3	2.9	1.0	2.8	1.2	1.8	2.1
Hand grip strength (right)	1.6	4.3	20.0	-2.5	-1.5	0.5	4.5	0.7	-1.8	0.4	-1.3
Happiness	1.6	1.9	5.4	0.4	0.8	1.4	2.3	1.9	0.7	1.4	1.2
Standing height	1.6	15.8	40.3	-6.3	-3.4	-0.6	-3.4	-4.0	-2.7	-5.8	-2.6
Peak expiratory flow (PEF)	1.6	3.8	20.1	-0.5	-0.2	0.1	-4.5	-2.4	-0.2	-2.0	-0.1
Blood Red Count	1.5	14.5	58.5	-0.6	-1.2	-1.0	7.7	5.3	-2.8	4.2	-1.1
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	3.0	-1.0	-1.7	-1.6	-0.9	-1.1	-1.4	-1.6	-1.7
Hair/balding pattern: Pattern 3	1.5	2.2	5.7	-2.2	-1.0	-0.9	2.4	-1.1	-1.3	-1.1	-0.9
Number of children fathered	1.5	1.7	4.5	-1.3	-1.0	-2.1	1.7	-0.9	-1.0	-0.4	-1.4
Tinnitus: Yes, now most or all of the time	1.5	1.7	6.9	-0.1	-1.3	-0.8	2.6	1.3	-1.1	1.1	-0.9
Prostate Cancer	1.4	2.0	5.2	-1.3	-0.1	-1.4	-1.9	-1.6	-0.2	-2.3	-0.6
Pulse wave peak to peak time	1.4	1.6	8.2	-0.2	1.3	0.3	2.9	0.7	1.1	1.0	0.5
Chest pain or discomfort	1.4	2.0	3.5	-1.9	-1.7	-0.7	1.8	-1.1	-1.3	-1.3	-1.1
Eye problems/disorders: Glaucoma	1.4	1.6	12.0	-0.2	-0.1	-0.0	3.5	0.7	0.2	0.7	-0.1
Illnesses of father: High blood pressure	1.4	1.7	3.6	-0.7	-1.5	-1.2	0.2	-0.9	-1.9	-1.2	-1.9
Height	1.3	25.2	67.2	-8.2	-3.7	-1.0	-5.2	-4.8	-2.9	-7.3	-2.7
Average weekly spirits intake	1.3	1.6	3.5	-1.2	-1.7	-1.0	1.0	-0.1	-1.9	-0.2	-1.7
Sensitivity / hurt feelings	1.3	2.3	5.2	2.2	1.1	1.3	0.6	2.0	0.9	2.3	0.8
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	3.3	-1.8	-0.7	-1.3	-0.7	-1.7	-0.2	-1.8	0.2
Medication: Ramipril	1.3	1.6	4.1	-1.6	-1.3	-2.0	1.4	0.5	-1.3	-0.4	-0.6
Heart disease (mother)	1.3	1.5	3.3	-1.4	-1.3	-0.6	-0.4	-1.2	-1.8	-1.2	-1.3
Smoking status: Current	1.3	2.0	5.4	0.0	-1.2	-1.7	-0.4	-1.4	-1.6	-1.2	-2.3
Medication: Atorvastatin	1.3	1.6	3.2	0.6	1.1	0.5	1.7	1.0	1.3	1.4	1.8
Bipolar Disorder or Schizophrenia	1.2	2.9	6.5	1.9	1.0	1.4	1.8	2.5	1.1	2.1	1.1
Schizophrenia (2018)	1.2	2.4	3.8	2.0	1.4	1.4	1.5	1.8	1.5	1.6	1.0
Cardiovascular Disease	1.2	3.9	11.4	0.4	1.6	1.4	3.4	2.0	1.4	2.0	2.3
Hair Pigment	1.2	34.1	139.2	11.8	4.3	0.4	-4.6	0.3	6.4	6.9	2.4
Current tobacco smoking	1.2	1.9	4.5	-0.1	-1.1	-1.8	-0.6	-1.5	-1.5	-1.2	-2.1
Medication: Lansoprazole	1.2	1.4	3.4	-0.1	-1.9	-1.1	-1.3	-1.5	-0.7	-0.8	-1.2
Illnesses of mother	1.2	1.5	2.6	0.2	1.4	1.3	0.4	1.2	1.6	1.2	1.5
Tense / ‘highly strung’	1.2	2.1	4.5	-1.8	-2.1	-0.9	1.0	-0.5	-2.1	-0.8	-1.3
Medication: Ibuprofen	1.2	1.4	2.3	-1.5	-0.8	-1.3	0.9	-0.6	-1.4	-1.0	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.7	-1.4	-1.2	-1.0	1.2	-0.8	-1.6	-0.5	-1.2
Supplements: Vitamin C	1.2	1.4	2.8	1.2	0.9	0.6	1.1	1.6	0.9	1.7	1.0
Loneliness, isolation	1.2	1.6	2.9	1.7	1.5	0.8	0.7	1.1	1.5	1.5	0.9
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.5	-1.4	-0.5	-1.9	-1.4	-1.0	0.3	-1.2	-0.3
Medication: Gliclazide	1.2	1.4	2.2	1.1	1.5	1.0	-0.9	1.1	1.2	1.0	1.5
Alzheimer’s Disease (including proxy)	1.1	1.6	3.0	-0.7	-1.6	-1.5	-0.6	-1.0	-1.5	-0.9	-1.7
Ulcerative Colitis	1.1	1.7	3.5	-1.8	-1.9	-0.7	-1.3	-0.4	-1.4	-1.2	-0.8
Tanning	1.1	13.0	20.5	-4.3	-4.1	-3.6	1.2	-2.4	-4.5	-3.5	-4.0
Time employed in main current job	1.1	1.2	1.8	1.3	0.8	1.1	0.6	1.1	1.3	1.3	1.1
Noisy workplace	1.1	1.3	2.7	-1.6	-1.2	-1.6	1.6	-0.5	-0.2	-0.8	-0.5
Mean time to correctly identify matches	1.1	2.1	4.1	-1.5	-1.7	-1.0	2.0	-0.9	-1.6	-0.5	-1.6
Medication for cholesterol	1.1	1.6	3.2	-1.0	-0.8	-1.8	-1.2	-1.5	-0.7	-1.6	-1.1
Medication: Paracetamol	1.1	1.8	3.3	-1.5	-1.8	-1.6	-0.3	-0.6	-1.7	-1.2	-1.1
Diastolic blood pressure, automated reading	1.1	3.6	7.2	0.9	2.0	0.8	2.7	2.1	1.4	2.1	2.2
Reaction Time	1.0	1.9	4.1	-1.6	-2.0	-0.7	1.9	-0.6	-1.6	-0.3	-1.3
HbA1C	1.0	1.1	2.5	1.1	1.6	0.8	-1.1	0.4	1.3	0.9	0.7
LDL Cholesterol	1.0	1.6	6.5	-0.8	-0.1	0.9	2.6	1.7	-0.5	1.3	0.3
Smoking Status	1.0	2.4	5.7	0.7	-1.3	-2.4	-0.7	-1.6	-1.6	-1.0	-2.3
Lung FEV1/FVC ratio	1.0	5.0	12.3	3.5	2.4	0.6	-3.4	-0.2	2.1	1.9	1.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	2.5	1.3	0.8	1.6	0.9	1.2	0.9	1.6	0.8
Fluid intelligence score	1.0	2.0	9.4	-1.0	0.3	-1.0	-3.1	-1.2	-0.5	-1.6	0.3
Health satisfaction	1.0	1.3	4.3	-1.1	-1.7	-0.8	2.1	0.3	-0.8	-0.2	-0.8
Number of self-reported non-cancer illnesses	1.0	1.7	4.2	0.7	0.8	-0.2	2.0	2.0	0.6	1.6	1.1
Ulcerative Colitis (UC)	0.9	1.6	7.1	-2.7	-1.5	-0.3	-0.2	-0.1	-1.4	-1.2	-0.3
Schizophrenia (2014)	0.9	2.1	4.7	2.2	1.0	1.1	1.0	2.0	1.1	1.7	0.6
Townsend deprivation index at recruitment	0.9	1.3	4.4	2.1	0.8	-0.3	0.9	1.3	0.3	1.5	-0.0
Relative age voice broke	0.9	1.4	3.5	-1.4	-1.2	-1.9	-1.0	-1.0	-0.6	-1.1	-0.6
Hayfever, allergic rhinitis or eczema	0.9	1.9	2.7	1.4	1.6	1.4	1.0	1.2	1.6	1.2	1.5
Had menopause	0.9	1.1	2.4	-0.4	-0.9	-0.7	-0.9	-1.2	-1.0	-1.2	-1.5
Asthma	0.9	1.8	7.9	0.3	0.3	1.3	2.8	1.4	-0.0	1.2	1.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	2.5	1.6	1.2	0.9	-0.2	0.5	1.2	1.2	1.0
Emphysema/chronic bronchitis	0.9	1.0	2.3	-1.5	-1.1	-0.7	0.2	-0.8	-0.7	-1.3	-0.9
Medication: Aspirin	0.9	1.2	5.8	-2.4	-0.9	-0.4	-0.2	-1.1	-0.8	-1.1	0.1
Knee pain experienced in last month	0.9	1.3	2.8	-0.5	-1.0	-1.5	0.0	-0.7	-1.7	-1.1	-1.6
Number of operations (self-reported)	0.9	1.3	3.4	-0.4	-1.0	-1.3	-0.8	-0.5	-1.6	-1.0	-1.9
Commuting to job workplace: Cycle	0.9	1.0	2.5	1.0	1.6	1.0	-0.5	0.0	1.5	0.5	1.1
Schizophrenia vs Biploar Disorder	0.8	1.0	2.2	1.1	1.5	0.8	0.8	0.9	1.2	0.7	0.7
Alzheimer’s Disease (in mother)	0.8	0.9	1.9	0.0	-0.7	-1.4	-0.9	-0.9	-1.0	-0.7	-1.3
Crohns Disease (2012)	0.8	1.3	3.7	-0.3	0.4	1.9	0.2	1.9	0.4	1.2	1.0
HDL Cholesterol	0.8	1.3	5.2	-2.3	-1.0	-1.0	0.1	-1.1	0.2	-1.3	0.5
Blood White Count	0.8	5.8	20.7	2.8	0.1	-1.1	-4.5	-3.1	-0.2	-2.4	-1.3
Heel T-Score	0.8	6.7	41.3	6.4	2.0	0.4	-0.2	0.9	0.5	2.5	-0.4
Relative age of first facial hair	0.8	1.6	5.6	1.0	-1.0	-2.4	-1.9	-1.1	-0.2	0.0	-0.6
Vitamin and mineral supplements	0.8	1.1	2.4	-0.4	-0.9	-0.1	-0.4	-1.4	-1.5	-1.0	-1.5
Medication: Co-codamol	0.8	0.9	2.8	1.3	-0.8	-1.3	-1.7	0.3	-0.5	-0.0	-0.5
Age when periods started (menarche)	0.8	1.9	7.2	-0.9	1.1	0.7	-1.0	0.7	2.0	-0.3	2.7
Impedance of leg (left)	0.8	4.1	11.8	0.3	2.3	1.9	-1.4	0.0	3.4	-0.0	3.2
Forced vital capacity (FVC)	0.8	3.0	14.7	-3.8	-1.4	2.1	-0.2	-1.1	-0.4	-1.2	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	8.7	3.0	1.0	0.4	-0.5	1.1	0.5	1.7	0.5
Father’s age at death	0.8	1.1	2.0	-0.7	-0.4	-1.1	-0.8	-1.4	-0.6	-1.4	-1.3
Qualifications: A levels/AS levels or equivalent	0.8	1.7	4.6	0.2	1.8	1.1	-0.4	0.8	1.9	0.4	2.1
Pulse wave reflection index	0.8	0.9	2.9	1.0	-1.3	-0.5	-1.7	0.1	-1.0	-0.2	-0.8
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.1	-0.2	-1.3	-0.6	1.3	-0.3	-1.4	-0.2	-1.4
Qualifications: nursing, teaching	0.8	1.3	6.4	-0.4	0.1	-0.2	-2.5	-1.4	0.2	-1.2	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	3.0	0.1	-0.7	-0.6	-0.5	-1.2	-0.8	-1.0	-1.7
Asthma (self-reported)	0.8	1.6	6.9	0.4	0.3	1.2	2.6	1.3	-0.1	1.2	1.1
Impedance of whole body	0.8	4.2	13.1	-0.4	1.6	2.1	-1.1	0.7	3.4	-0.2	3.6
Respiratory disease	0.7	1.6	6.8	-1.3	-1.6	0.5	2.6	-0.1	-1.2	-0.4	-0.3
Lung FVC	0.7	3.4	10.0	-2.2	-0.5	3.2	2.9	0.2	0.3	1.3	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	7.5	2.7	0.6	-0.2	-0.2	1.1	0.3	1.6	0.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.4	-0.2	-0.9	-1.9	-0.5	-1.1	-0.4	-0.8	-0.7
Financial difficulties in last 2 years	0.7	1.0	2.0	-1.0	-1.2	-1.1	-0.0	-0.9	-1.0	-0.8	-1.4
Heart attack	0.7	0.9	2.9	-1.7	0.5	0.8	0.3	0.2	1.2	0.3	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.3	0.4	0.8	0.6	-1.5	-0.4	1.1	-0.3	1.0
Forced vital capacity (FVC), Best measure	0.7	2.5	10.4	-3.2	-0.6	2.7	0.1	-0.3	0.0	-0.6	1.3
Wheeze or whistling in the chest in last year	0.7	1.3	9.4	-0.5	-0.2	0.3	3.1	0.3	-0.4	0.2	-0.1
Breast cancer (self-reported)	0.7	0.8	1.8	-1.3	-0.7	-0.6	-0.3	-1.2	-0.9	-1.2	-0.6
Medication: Blood pressure	0.7	1.4	2.3	1.2	1.1	0.9	1.2	1.5	0.8	1.1	1.3
Ever smoked	0.7	1.3	3.5	-0.4	-1.1	-1.9	-0.3	-0.9	-1.1	-0.7	-1.7
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.7	-1.6	0.5	0.7	0.2	0.1	1.2	0.3	1.5
Bipolar Disorder (2018)	0.6	0.9	3.0	0.6	-0.1	0.6	1.0	1.7	-0.0	1.4	0.5
Intelligence (Savage-Jansen 2018)	0.6	1.8	7.2	-0.6	1.1	1.6	-2.7	-0.4	0.5	-0.9	1.3
Verbal and Numeric Reasoning (VNR)	0.6	1.5	5.7	-0.5	1.5	1.0	-2.4	-0.6	0.5	-0.8	1.2
Number of treatments/medications taken	0.6	1.1	3.3	-1.8	-1.2	-0.7	0.3	-0.3	-1.5	-0.7	-0.6
Hearing difficulty/problems: Yes	0.6	0.9	2.6	0.5	-0.1	-0.3	1.5	1.6	-0.5	1.4	0.1
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.0	0.6	-0.9	-0.3	-1.2	-0.7	-0.7	-0.4	-1.4
Ever had hysterectomy (womb removed)	0.6	0.7	2.2	-1.5	-0.2	-0.6	0.5	-1.1	-0.1	-0.9	-0.7
Impedance of leg (right)	0.6	3.1	9.1	-0.2	1.9	1.5	-0.9	-0.3	3.0	-0.4	2.9
High blood pressure	0.6	1.7	2.9	0.3	1.6	0.9	1.5	1.7	0.9	1.2	1.7
Past tobacco smoking	0.6	1.1	3.5	0.1	0.8	1.9	-0.6	0.9	0.8	0.6	1.6
Had other major operations	0.6	0.8	1.3	-0.7	-0.9	-0.8	0.0	-1.0	-0.9	-1.1	-1.1
Allergy	0.6	1.3	5.1	-0.4	-1.0	-1.1	-2.3	-0.9	-0.6	-0.9	-1.2
Impedance of arm (left)	0.6	2.7	9.4	-0.5	0.9	1.4	-0.9	0.8	2.7	-0.4	3.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	2.4	0.7	1.5	0.3	0.6	1.3	0.6	1.1	0.7
Migraine (self-reported)	0.6	0.7	4.3	-2.1	-0.9	-0.6	0.3	0.2	-0.1	-0.3	0.3
Commuting to job workplace: Walk	0.6	0.7	3.0	-1.1	-0.4	-0.1	1.7	-0.6	-0.5	-0.1	-0.4
Average weekly champagne plus white wine intake	0.6	0.9	4.1	-0.4	-0.1	-0.9	-2.0	-0.6	0.5	-1.1	0.2
Miserableness	0.6	1.0	2.1	0.0	-1.3	-1.3	0.6	-0.5	-1.3	-0.5	-1.5
Age started oral contraceptive pill	0.6	0.8	1.4	1.2	1.0	0.3	0.7	1.2	0.5	1.0	0.7
Neuroticism (Nagel 2018)	0.5	1.2	3.1	1.2	0.6	1.8	1.1	1.4	0.1	1.3	0.1
Worry (Nagel 2018)	0.5	1.0	5.3	-0.6	-0.2	2.3	1.1	0.9	-0.4	0.6	0.2
Irritable Bowel Disease (IBD)	0.5	1.1	4.6	-2.1	-0.6	1.2	0.3	1.3	-0.4	-0.0	0.8
Age at First Birth	0.5	0.7	1.7	-1.3	-0.5	-0.1	-1.3	-0.8	-0.5	-1.0	-0.0
Blood Platelet Count	0.5	5.6	14.5	-3.0	-0.7	-2.3	-2.8	-2.7	-0.1	-3.8	0.6
Hypothyroidism (self reported)	0.5	1.1	3.1	0.2	0.4	1.3	-1.8	1.0	0.8	1.0	1.2
Angina	0.5	0.7	1.5	-1.2	0.4	-1.2	1.1	-0.4	0.6	-0.4	0.7
Medication for hormone replacement therapy	0.5	0.5	1.9	0.7	-0.5	0.4	-1.4	-0.5	-0.7	-0.1	-0.8
Supplements: Zinc	0.5	0.5	1.3	1.0	0.6	-0.8	0.0	0.3	1.2	0.5	0.6
Diabetes (father)	0.5	0.6	1.2	-0.5	-1.1	-0.9	-0.2	-0.5	-0.9	-0.9	-0.9
Medication: Levothyroxine sodium	0.5	0.8	2.0	0.7	-0.0	0.6	-1.2	1.3	0.3	1.4	0.6
Sitting height	0.5	3.7	15.7	-1.9	-1.3	0.8	-4.0	-1.4	-0.9	-2.3	-0.6
Nervous feelings	0.5	0.9	4.1	-2.0	-0.8	1.2	0.7	0.1	-0.6	-0.3	0.2
Neuroticism score	0.5	1.0	4.1	0.7	-0.2	0.3	2.0	1.4	-0.2	1.2	0.1
Impedance of arm (right)	0.5	2.5	8.0	-0.8	0.6	1.3	-1.8	0.2	2.2	-1.1	2.8
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.7	-0.2	-0.8	-1.3	-1.0	-0.8	-0.9	-0.9	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	6.0	-2.5	-0.4	2.3	0.1	-0.4	0.3	-0.0	1.3
Medication: Paracetamol	0.5	0.9	2.0	-1.0	-1.3	-1.4	-0.5	-0.4	-0.9	-0.7	-0.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.4	0.6	-0.9	0.8	-1.1	-0.6	-0.4	-0.6	-1.5
Number of full brothers	0.5	0.6	3.6	0.1	0.6	-1.9	0.5	0.2	0.3	0.4	0.3
Worry too long after embarrassment	0.5	0.8	3.5	-0.8	-1.0	-0.3	1.9	0.7	-0.6	0.4	-0.0
Medication: Blood pressure	0.5	0.9	1.9	-1.4	-0.3	-1.4	-0.5	-0.8	-0.9	-1.1	-0.1
Angina (self-reported)	0.5	0.7	1.8	-1.0	0.6	-1.4	1.1	-0.4	0.7	-0.4	0.7
Illnesses of siblings: Diabetes	0.5	0.6	3.9	0.4	-0.4	-0.6	-2.0	-0.1	-0.3	-0.2	0.0
Wears glasses or contact lenses	0.5	0.6	1.4	0.9	1.2	-0.2	1.1	0.8	0.3	0.8	0.2
Hearing aid user	0.5	0.6	1.3	-0.8	-1.1	-1.1	0.9	-0.0	-0.5	-0.5	-0.1
Financial situation satisfaction	0.5	0.6	2.5	0.9	0.1	0.3	1.6	0.7	0.2	0.7	0.4
Supplements: Fish oil (including cod liver oil)	0.5	0.7	4.8	-0.1	0.2	-0.1	2.2	0.5	0.5	0.3	0.5
Myopia	0.5	0.7	1.9	1.0	1.2	1.4	-0.4	0.5	0.7	0.3	0.6
Vascular/heart problems diagnosed by doctor	0.5	1.4	3.6	0.2	-1.2	-0.3	-1.9	-1.4	-0.8	-1.1	-1.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.1	1.0	0.9	-0.7	0.9	1.0	0.6	0.9	-0.1
Pain experienced in last month	0.5	0.8	1.4	1.2	1.2	0.7	0.2	1.1	0.5	0.9	1.0
Depression (Nagel 2018)	0.4	0.6	1.9	1.4	0.9	1.1	-0.4	0.6	0.2	0.5	0.1
Breast Cancer	0.4	0.8	3.0	1.2	-0.6	-1.7	-0.8	0.4	-0.9	0.2	-0.6
Primary Biliary Cirrhosis	0.4	0.6	1.8	-1.3	-0.9	-0.3	0.4	1.3	-0.4	0.5	0.2
Waist Hip Ratio (WHR)	0.4	1.7	7.7	0.7	-1.4	-0.3	2.8	0.8	-1.1	0.9	-0.9
Taking other prescription medications	0.4	0.6	2.0	-1.4	-1.0	-0.1	0.0	-0.4	-0.9	-0.7	-0.6
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.2	0.1	1.0	0.2	-0.7	-1.1	0.8	-0.8	0.1
Qualifications: CSEs or equivalent	0.4	0.6	2.3	-0.5	0.3	1.5	0.6	-1.1	-0.2	-0.5	-0.1
Supplements: Glucosamine	0.4	0.6	1.5	1.2	0.7	-0.6	-1.2	0.6	0.3	0.4	0.6
Medication: Atenolol	0.4	0.5	2.2	-0.3	-0.1	-1.5	1.0	-0.1	0.4	-0.1	0.7
Number of incorrect matches in round	0.4	0.7	2.4	0.0	-1.3	0.6	-1.6	-0.2	-0.7	-0.6	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.4	-0.6	-0.9	-1.1	-0.9	-0.4	-1.2	-0.3	-0.7
Hair/balding pattern: Pattern 2	0.4	0.5	1.0	0.4	-1.0	-1.0	-0.0	-0.7	-0.6	-0.3	-1.0
Illnesses of siblings	0.4	0.5	1.5	-0.8	-0.2	0.7	-0.5	-1.1	-0.1	-1.2	-0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	5.2	-2.3	-0.6	2.0	-0.1	-0.4	0.2	0.0	1.1
Length of working week for main job	0.4	0.4	0.9	0.2	0.3	0.6	1.0	0.9	0.5	0.8	-0.1
Exposure to tobacco smoke at home	0.4	0.5	2.3	1.5	-0.4	-0.4	-0.6	0.5	0.1	0.8	0.1
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.7	0.3	-0.4	-0.2	-1.6	-0.5	-0.1	-0.5	-0.4
Medication: Amlodipine	0.4	0.6	1.7	-1.1	-0.4	-0.3	-0.2	-0.8	-0.9	-1.3	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.1	-0.4	-0.7	-0.3	-0.3	-0.6	-0.9	-0.8	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.8	0.2	0.5	-0.3	1.3	0.1	1.0	0.6	0.7
Hypertension (Self-reported)	0.4	1.1	2.3	0.2	1.3	0.4	1.3	1.5	0.5	1.0	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.3	0.4	-0.7	0.4	1.1	-0.3	-0.7	-0.1	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.2	0.1	-0.6	-0.8	-0.7	-1.5	0.1	-1.2	-0.1
Mineral and other dietary supplements	0.4	0.5	1.8	-0.2	-0.4	0.0	-1.3	-1.0	-0.5	-0.5	-0.8
Guilty feelings	0.4	0.7	4.0	0.3	-0.3	-0.3	2.0	0.6	-0.4	0.5	-0.6
Alcohol drinker status: Never	0.4	0.5	1.7	0.1	-1.1	-0.2	0.5	-0.5	-0.9	-0.3	-1.3
Heart disease (siblings)	0.4	0.5	2.5	-0.4	0.1	-0.7	1.6	0.4	0.1	0.7	-0.0
Alzheimer’s Disease (in father)	0.3	0.4	0.8	-0.3	-0.8	-0.6	-0.6	-0.6	-0.9	-0.5	-0.4
Coronary Artery Disease (CAD)	0.3	0.4	0.8	-0.9	-0.3	0.9	0.9	0.3	0.0	0.4	0.6
Lupus	0.3	0.5	2.6	-1.6	-0.4	0.5	0.1	0.3	0.4	0.1	1.0
Neuroticism (2016)	0.3	0.5	1.3	-0.4	-0.7	-0.4	-0.4	-0.3	-1.0	-0.5	-1.1
Rheumatoid Arthritis	0.3	0.4	0.8	0.8	0.7	0.4	-0.9	0.5	0.7	0.6	0.5
Blood Eosinophil Count	0.3	2.1	5.3	0.2	2.2	0.8	0.8	-1.3	2.3	-0.5	1.8
Allergy or Eczema	0.3	0.8	1.7	1.1	1.3	0.6	0.5	0.3	1.3	0.8	0.9
Multivitamins +/- minerals	0.3	0.4	0.9	-0.3	0.3	-0.8	-0.3	0.5	0.9	0.0	1.0
Alcohol usually taken with meals	0.3	0.5	1.4	-0.2	0.4	1.2	-1.1	-0.1	0.7	0.1	1.0
Qualifications: None of the above	0.3	0.6	2.3	0.8	-0.5	-1.5	0.5	0.4	-0.4	0.7	-0.7
Alcohol intake versus 10 years previously	0.3	0.5	1.1	-0.3	0.9	-0.2	1.1	0.6	0.8	0.4	0.8
Breastfed as a baby	0.3	0.3	1.6	1.3	0.2	-0.3	-0.3	0.4	0.7	0.2	0.0
Hair/balding pattern: Pattern 4	0.3	0.7	1.4	-1.2	0.1	1.0	0.9	-0.3	-0.6	-1.0	-1.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.6	0.3	0.1	1.1	-1.3	0.8	0.5	1.2	0.4
Birth weight	0.3	0.5	1.6	-1.0	-0.4	-1.3	1.1	0.6	-0.1	-0.0	-0.4
Qualifications: College or University degree	0.3	0.9	2.2	-0.4	0.9	1.0	-1.3	0.2	1.1	-0.2	1.5
Medication: Omeprazole	0.3	0.4	1.4	0.2	0.1	-1.2	0.6	0.2	-0.5	-0.0	-1.0
Medication: Seretide 50 evohaler	0.3	0.4	1.0	0.5	-0.0	-1.0	0.6	-0.5	-0.8	-0.5	-0.7
Pulse rate, automated reading	0.3	1.0	3.0	-1.7	-1.1	0.1	0.7	-0.2	-1.7	-0.3	-0.5
Suffer from ‘nerves’	0.3	0.5	2.1	-0.2	-0.2	1.4	-0.9	-0.6	0.0	-0.4	-0.4
Overall health rating	0.3	0.7	3.3	0.1	-0.5	-0.3	1.8	1.1	-0.5	0.3	-0.2
Age at last live birth	0.3	0.4	0.9	-0.9	-0.8	-0.9	-0.1	0.7	-0.4	-0.2	0.3
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.8	0.8	0.6	-0.0	-0.9	0.8	-0.2	0.6	0.5
Illnesses of father: Heart disease	0.3	0.4	2.0	0.2	-0.1	-1.4	-0.5	-0.5	-0.7	-0.5	0.1
Back pain experienced in last month	0.3	0.5	1.6	-0.3	0.3	1.1	-1.3	-0.3	0.4	-0.3	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	1.9	-0.7	0.1	1.4	0.7	-0.7	0.5	0.2	0.8
Ever taken oral contraceptive pill	0.3	0.3	1.1	0.7	1.0	-0.5	-0.6	0.0	0.3	0.2	0.1
Medication: Bendroflumethiazide	0.3	0.5	1.2	0.2	1.1	-1.0	-0.9	0.3	0.3	0.2	0.8
Average weekly beer plus cider intake	0.3	0.4	1.0	1.0	-0.4	-0.6	-0.2	0.6	-0.5	0.6	-0.8
Ever depressed for a whole week	0.3	0.4	0.9	-0.7	-1.0	-0.3	-0.4	-0.5	-0.7	-0.7	0.1
Unable to work because of sickness or disability	0.3	0.4	1.2	-1.1	-0.6	-0.5	0.3	-0.7	-0.2	-0.8	-0.4
Depressed Affect (Nagel 2018)	0.2	0.4	1.3	1.1	-0.2	-0.4	0.4	0.2	-0.8	0.2	-1.0
Neuroticism	0.2	0.5	2.0	0.3	0.2	0.2	1.4	1.0	-0.3	0.8	0.2
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.8	0.5	0.2	0.2	0.6	0.9	-0.2	0.6	-0.2
Severe depression (siblings)	0.2	0.3	0.9	1.0	0.5	0.1	-0.3	-0.2	0.7	0.1	0.4
Fed-up feelings	0.2	0.4	1.6	1.2	-0.6	-0.6	0.3	0.6	-0.5	0.4	-0.5
Serious illness, injury or assault to yourself	0.2	0.2	0.6	-0.8	0.4	0.4	0.2	-0.6	-0.0	-0.7	-0.1
High blood pressure (mother)	0.2	0.2	0.9	-0.7	-0.0	0.4	0.4	0.4	-0.3	0.3	0.9
Hearing difficulty/problems with background noise	0.2	0.3	1.1	-0.4	-0.6	-0.6	-0.3	0.8	-1.0	0.1	-0.1
Prospective memory result	0.2	0.3	1.0	0.7	-0.1	1.0	0.6	0.5	0.2	0.4	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.4	0.6	0.3	1.2	-0.3	0.2	0.2	0.1	0.3
Birth weight of first child	0.2	0.4	1.8	1.4	0.4	-0.0	-0.9	0.3	0.3	0.1	-0.1
Comparative body size at age 10	0.2	0.5	2.0	1.4	0.8	0.2	0.3	-0.2	-0.3	0.1	-1.0
Neck or shoulder pain in last month	0.2	0.3	0.6	0.4	-0.8	-0.5	-0.7	-0.7	-0.2	-0.5	-0.6
Number of full sisters	0.2	0.3	1.4	0.4	0.1	0.0	1.2	0.3	0.4	0.3	0.3
Had major operations	0.2	0.3	1.0	-0.2	0.1	-0.4	-0.1	1.0	-0.1	0.8	0.3
Leg pain on walking	0.2	0.2	1.1	0.3	-0.6	-0.2	0.1	-0.3	-0.5	-0.1	-1.1
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.8	-0.3	0.7	0.1	-0.4	-0.1	0.3	0.1	0.9
Smoking status: Previous	0.2	0.4	1.5	0.2	-0.1	-1.2	0.9	-0.5	0.0	-0.1	-0.5
Mood swings	0.2	0.3	0.7	0.8	0.1	-0.5	0.6	0.9	-0.3	0.7	-0.3
Long-standing illness, disability or infirmity	0.2	0.4	1.3	0.7	-0.7	-1.1	0.9	0.0	0.1	0.0	-0.2
Osteoarthritis (self-reported)	0.2	0.3	0.7	0.6	0.5	-0.1	0.3	0.8	0.6	0.4	0.6
Mother’s age at death	0.2	0.2	0.7	0.8	0.6	-0.4	-0.2	0.3	0.4	0.1	-0.1
Commuting to job workplace: Public transport	0.2	0.3	0.6	-0.8	-0.6	-0.3	0.0	-0.3	-0.2	-0.8	-0.4
Pack years of smoking	0.2	0.2	0.5	0.1	-0.3	-0.2	-0.4	-0.6	-0.7	-0.3	-0.7
Average weekly fortified wine intake	0.1	0.1	0.2	0.3	-0.0	-0.5	0.4	0.4	0.1	0.5	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.5	0.7	-0.1	-0.0	-0.3	0.1	-0.4	0.3	-0.6
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.6	0.8	-0.3	0.3	-0.4	-0.2	0.2	-0.2	0.1
Pain all over the body in last month	0.1	0.1	0.5	-0.1	-0.1	-0.7	0.3	0.1	0.0	0.3	0.2
Depression (self-reported)	0.1	0.1	0.5	0.4	0.4	0.7	-0.2	0.1	-0.1	-0.1	-0.2
Loud music exposure frequency	0.1	0.1	0.7	0.8	0.2	-0.1	0.2	0.1	0.5	0.1	-0.2
High blood pressure (siblings)	0.1	0.1	0.3	0.5	-0.4	-0.0	-0.2	0.4	-0.4	0.4	0.1
Age at first live birth	0.1	0.3	0.7	-0.5	-0.2	-0.7	-0.2	0.8	0.2	0.1	0.8
Alcohol intake frequency.	0.1	0.2	0.7	0.2	0.0	-0.0	-0.1	-0.8	0.0	-0.7	-0.6
Average weekly red wine intake	0.1	0.2	0.5	0.5	0.2	-0.4	0.7	0.3	0.3	0.6	-0.2
Pack years adult smoking proportion	0.0	0.1	0.2	0.4	0.2	0.2	-0.1	-0.3	-0.4	0.0	-0.3

Hub : Genes

CBX1

Models

Trait associations