[Hub]/) : Traits : Arm fat percentage (left) :

chr19:33,182,320-34,959,979

Best TWAS P=1.6e-20 · Best GWAS P=3.28e-19 conditioned to 0.0556

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PEPD 0.32 0.27 enet 22 0.38 1.2e-49 1.6 5.5 3.0e-08 0.48 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous PEPD 0.30 0.25 lasso 6 0.26 2.5e-21 6.0 5.6 2.8e-08 0.73 1.00 0.00 FALSE
3 GTEx Breast Mammary Tissue PEPD 0.16 0.06 lasso 4 0.04 3.5e-03 6.0 6.5 7.1e-11 0.78 0.36 0.60 FALSE
4 GTEx Colon Transverse PEPD 0.14 0.16 lasso 2 0.13 1.2e-06 6.0 5.9 3.8e-09 0.71 0.61 0.24 FALSE
5 GTEx Esophagus Mucosa PEPD 0.37 0.32 enet 20 0.39 9.5e-28 6.0 7.9 2.0e-15 0.87 0.02 0.98 FALSE
6 METSIM Adipose CHST8 0.22 0.17 lasso 4 0.17 3.7e-25 6.0 6.2 6.2e-10 0.73 1.00 0.00 FALSE
7 METSIM Adipose PEPD 0.19 0.18 lasso 5 0.17 2.3e-24 6.0 6.0 1.7e-09 0.73 1.00 0.00 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma PEPD 0.06 0.01 blup 114 0.04 2.6e-04 8.9 7.7 1.7e-14 0.84 0.01 0.97 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma PEPD 0.13 0.06 blup 113 0.10 1.2e-06 5.1 9.3 1.6e-20 0.86 0.01 0.99 TRUE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PEPD 0.04 0.05 blup 113 0.03 1.9e-04 -6.2 5.8 7.7e-09 0.53 0.53 0.20 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma PEPD 0.05 0.03 blup 113 0.05 7.1e-07 6.4 5.5 4.3e-08 0.69 0.06 0.94 FALSE
12 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PEPD 0.16 0.07 lasso 3 0.05 3.1e-03 8.9 8.6 6.5e-18 0.95 0.01 0.97 FALSE