Best TWAS P=7.58e-08 · Best GWAS P=8.75e-08 conditioned to 0.0845
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | OXER1 | 0.31 | 0.03 | lasso | 8 | 0.05 | 3.5e-04 | -3.4 | 5.4 | 7.6e-08 | -0.80 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Pancreas | HAAO | 0.27 | 0.32 | lasso | 2 | 0.29 | 1.4e-12 | -5.2 | -5.2 | 1.7e-07 | 1.00 | 0.01 | 0.99 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | OXER1 | 0.05 | 0.09 | lasso | 3 | 0.08 | 6.3e-10 | -5.2 | 5.2 | 2.0e-07 | -1.00 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | OXER1 | 0.05 | 0.04 | lasso | 2 | 0.03 | 8.9e-05 | -5.0 | 5.3 | 1.2e-07 | -0.95 | 0.01 | 0.98 | FALSE |