Best TWAS P=9.54e-08 · Best GWAS P=3.28e-10 conditioned to 6.31e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CRIPT | 0.12 | 0.10 | lasso | 3 | 0.09 | 7.1e-08 | -4.4 | -5.1 | 3.1e-07 | 0.12 | 0.97 | 0.02 | FALSE |
| 2 | GTEx | Muscle Skeletal | CRIPT | 0.14 | 0.05 | enet | 25 | 0.08 | 1.8e-08 | -3.8 | -5.2 | 1.6e-07 | 0.11 | 0.97 | 0.02 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | PIGF | 0.14 | 0.08 | lasso | 4 | 0.07 | 1.7e-04 | -5.3 | 5.2 | 2.3e-07 | -0.06 | 0.17 | 0.69 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | CRIPT | 0.10 | 0.06 | blup | 66 | 0.07 | 5.6e-05 | -3.7 | -5.3 | 9.5e-08 | 0.09 | 0.47 | 0.23 | TRUE |