Best TWAS P=2.54e-11 · Best GWAS P=2.33e-12 conditioned to 0.0036
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 1.3e-03 | 6.0 | -6.1 | 1.1e-09 | 0.04 | 0.16 | 0.82 | TRUE |
2 | YFS | Blood | TAL1 | 0.03 | 0.02 | bslmm | 402 | 0.02 | 2.6e-06 | 7.0 | -6.7 | 2.5e-11 | -0.90 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | TAL1 | 0.03 | 0.02 | blup | 75 | 0.02 | 9.2e-03 | 5.9 | 5.6 | 2.7e-08 | 0.87 | 0.02 | 0.82 | FALSE |