[Hub]/) : Traits : Arm fat percentage (left) :

chr9:14,857,740-16,758,776

Best TWAS P=1.34e-30 · Best GWAS P=1.3e-25 conditioned to 0.617

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CCDC171 0.18 0.05 lasso 5 0.08 2.2e-05 -3.3 -5.2 1.6e-07 0.31 0.34 0.06 FALSE
2 GTEx Artery Tibial CCDC171 0.10 0.09 enet 9 0.12 7.2e-10 4.7 -6.2 5.2e-10 0.60 0.91 0.08 FALSE
3 GTEx Brain Caudate basal ganglia CCDC171 0.30 0.18 lasso 4 0.23 2.4e-07 9.0 -10.0 1.1e-23 0.95 0.04 0.96 FALSE
4 GTEx Brain Cerebellar Hemisphere CCDC171 0.46 0.19 lasso 7 0.23 1.3e-06 -10.5 -11.5 1.3e-30 0.91 0.03 0.97 TRUE
5 GTEx Brain Cerebellum CCDC171 0.46 0.22 lasso 7 0.15 3.4e-05 -10.2 -10.7 1.1e-26 0.97 0.02 0.98 FALSE
6 GTEx Brain Cortex CCDC171 0.26 0.15 lasso 2 0.16 2.8e-05 -8.6 -9.4 3.7e-21 0.92 0.06 0.91 FALSE
7 GTEx Brain Frontal Cortex BA9 CCDC171 0.27 0.18 enet 10 0.19 8.3e-06 9.1 -9.0 3.4e-19 0.83 0.07 0.88 FALSE
8 GTEx Brain Hypothalamus CCDC171 0.32 0.17 enet 6 0.09 4.0e-03 -10.5 -8.9 5.2e-19 0.91 0.03 0.90 FALSE
9 GTEx Breast Mammary Tissue CCDC171 0.21 0.01 lasso 5 0.03 1.5e-02 8.1 -5.5 4.6e-08 0.55 0.36 0.22 FALSE
10 GTEx Lung CCDC171 0.13 0.03 enet 9 0.01 5.0e-02 6.0 -7.7 1.0e-14 0.72 0.46 0.27 FALSE
11 GTEx Nerve Tibial CCDC171 0.25 0.16 lasso 6 0.14 2.1e-10 -10.0 -10.0 1.5e-23 0.96 0.13 0.87 FALSE
12 GTEx Ovary CCDC171 0.21 0.19 lasso 4 0.16 7.7e-05 8.8 8.5 2.7e-17 -0.85 0.18 0.43 FALSE
13 GTEx Pituitary CCDC171 0.28 0.16 enet 29 0.12 5.2e-04 9.0 -9.5 2.8e-21 0.90 0.19 0.75 FALSE
14 GTEx Skin Sun Exposed Lower leg CCDC171 0.14 0.09 enet 13 0.12 1.9e-10 8.8 -6.7 2.1e-11 0.63 0.99 0.01 FALSE
15 METSIM Adipose CCDC171 0.03 0.00 blup 828 0.01 4.0e-02 9.0 -8.6 1.2e-17 0.79 0.19 0.60 FALSE
16 ROSMAP Brain Pre-frontal Cortex CCDC171 0.14 0.11 enet 21 0.11 8.3e-14 9.2 -9.6 1.1e-21 0.81 0.90 0.10 FALSE
17 The Cancer Genome Atlas Soft Tissue Sarcoma C9orf93 0.06 0.05 lasso 3 0.03 5.3e-03 8.2 -7.0 2.6e-12 0.70 0.14 0.22 TRUE