Best TWAS P=2.45e-16 · Best GWAS P=1.5e-19 conditioned to 5.91e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -5.3 | 6.2 | 4.9e-10 | -0.66 | 0.71 | 0.12 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.7 | 8.2 | 2.4e-16 | -0.48 | 0.36 | 0.64 | TRUE |