Best TWAS P=3.66e-09 · Best GWAS P=3.45e-06 conditioned to 1.24e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | DCAF4 | 0.23 | 0.07 | enet | 30 | 0.13 | 4.3e-07 | 3.6 | 5.3 | 9.0e-08 | -0.11 | 0.04 | 0.63 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | RP11-109N23.6 | 0.14 | 0.11 | enet | 15 | 0.13 | 2.2e-07 | -3.9 | 5.2 | 1.7e-07 | -0.14 | 0.02 | 0.78 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | DCAF4 | 0.18 | 0.01 | enet | 10 | 0.06 | 3.0e-03 | 4.1 | 5.9 | 3.7e-09 | -0.05 | 0.01 | 0.20 | TRUE |
| 4 | GTEx | Esophagus Mucosa | DCAF4 | 0.30 | 0.19 | enet | 35 | 0.23 | 1.3e-15 | 4.1 | 5.1 | 2.8e-07 | -0.05 | 0.02 | 0.82 | FALSE |
| 5 | GTEx | Esophagus Mucosa | ZFYVE1 | 0.10 | 0.00 | lasso | 7 | 0.00 | 2.0e-01 | 4.1 | 5.4 | 5.7e-08 | -0.12 | 0.02 | 0.38 | FALSE |