TWAS
hub
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Models
Genes
Traits
[Hub]/) :
Traits
:
Arm fat mass (left)
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chr14:72,695,406-74,192,791
Best TWAS P=3.66e-09 · Best GWAS P=3.45e-06 conditioned to 1.24e-05
72.8M
73M
73.2M
73.4M
73.6M
73.8M
74M
74.2M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Esophagus Gastroesophageal Junction
DCAF4
0.18
0.01
enet
10
0.06
3.0e-03
4.1
5.9
3.7e-09
-0.05
0.01
0.20
TRUE
5
GTEx
Esophagus Mucosa
ZFYVE1
0.10
0.00
lasso
7
0.00
2.0e-01
4.1
5.4
5.7e-08
-0.12
0.02
0.38
FALSE
1
GTEx
Adipose Visceral Omentum
DCAF4
0.23
0.07
enet
30
0.13
4.3e-07
3.6
5.3
9.0e-08
-0.11
0.04
0.63
FALSE
2
GTEx
Adipose Visceral Omentum
RP11-109N23.6
0.14
0.11
enet
15
0.13
2.2e-07
-3.9
5.2
1.7e-07
-0.14
0.02
0.78
FALSE
4
GTEx
Esophagus Mucosa
DCAF4
0.30
0.19
enet
35
0.23
1.3e-15
4.1
5.1
2.8e-07
-0.05
0.02
0.82
FALSE