Best TWAS P=3.41e-41 · Best GWAS P=7.22e-157 conditioned to 7.58e-76
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FTO | 0.11 | 0.00 | bslmm | 739 | 0.02 | 1.6e-03 | -1.3 | 12.6 | 1.2e-36 | 0.38 | 0.09 | 0.55 | TRUE |
| 2 | GTEx | Muscle Skeletal | RBL2 | 0.11 | 0.00 | lasso | 5 | 0.00 | 2.9e-01 | 3.0 | -6.6 | 5.0e-11 | -0.10 | 0.28 | 0.23 | FALSE |
| 3 | GTEx | Testis | AKTIP | 0.19 | 0.00 | enet | 26 | 0.00 | 1.9e-01 | 2.1 | 13.4 | 3.4e-41 | 0.51 | 0.03 | 0.40 | TRUE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | FTO | 0.27 | 0.16 | enet | 13 | 0.14 | 6.7e-05 | -2.5 | 10.5 | 1.0e-25 | 0.33 | 0.11 | 0.32 | TRUE |