TWAS
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Genes
Traits
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Traits
:
Arm fat mass (left)
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chr19:3,391,883-4,821,612
Best TWAS P=6.82e-08 · Best GWAS P=1.19e-09 conditioned to 0.00136
3.4M
3.6M
3.8M
4M
4.2M
4.4M
4.6M
4.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Colon Sigmoid
MAP2K2
0.2
0.11
lasso
3
0.13
3e-05
-4.9
-5.4
6.8e-08
0.71
0.02
0.85
TRUE