Best TWAS P=2.36e-08 · Best GWAS P=2.06e-08 conditioned to 0.00772
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Caudate basal ganglia | SLC22A3 | 0.15 | 0.10 | enet | 39 | 0.11 | 0.00056 | -4.7 | -5.6 | 2.4e-08 | 0.64 | 0.18 | 0.55 | TRUE |
2 | GTEx | Skin Not Sun Exposed Suprapubic | SLC22A3 | 0.15 | 0.05 | lasso | 9 | 0.05 | 0.00099 | -3.8 | -5.2 | 2.2e-07 | 0.82 | 0.02 | 0.98 | FALSE |